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1. (WO2013153196) COMPOUNDS WHICH INHIBIT NEURONAL EXOCYTOSIS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2013/153196    International Application No.:    PCT/EP2013/057674
Publication Date: 17.10.2013 International Filing Date: 12.04.2013
IPC:
A61K 8/64 (2006.01), C07K 7/06 (2006.01)
Applicants: LUBRIZOL ADVANCED MATERIALS, INC. [US/US]; 9911 Brecksville Road Cleveland, Ohio 44141-3247 - USA (US)
Inventors: FERRER MONTIEL, Antonio; (ES).
FERNÁNDEZ BALLESTER, Gregorio; (ES).
GARCÍA ANTÓN, José María; (ES).
CARREÑO SERRAÏMA, Cristina; (ES).
ALMIÑANA DOMENECH, Núria; (ES).
DELGADO GONZÁLEZ, Raquel; (ES)
Agent: CARBONELL VALLÈS, Enric; ABG Patentes, S.L. Avda. de Burgos, 16D Edificio EUROMOR E-28036 Madrid (ES)
Priority Data:
12382145.6 13.04.2012 EP
61/652,624 29.05.2012 US
Title (EN) COMPOUNDS WHICH INHIBIT NEURONAL EXOCYTOSIS
(FR) COMPOSÉS INHIBANT L'EXOCYTOSE NEURONALE
Abstract: front page image
(EN)Compounds of general formula (I): R1-Wn-Xm-AA1-AA2-AA3-AA4-AA5-AA6-Yp-Zq-R2 (I ) their stereoisomers, mixtures thereof, their cosmetically or pharmaceutically acceptable salts and/or its functionally equivalent variants, preparation processes, cosmetic or pharmaceutical compositions which contain them and their use in medicine, particularly in the treatment and/or prevention of pain, inflammation, itching, neurological, compulsive and/or neuropsychiatric diseases and/or disorders and in processes of treatment and/or care of the skin, hair and/or mucous membranes mediated by neuronal exocytosis.
(FR)La présente invention concerne des composés de formule générale (I) : R1-Wn-Xm-AA1-AA2-AA3-AA4-AA5-AA6-Yp-Zq-R2 (I) leurs stéréoisomères, leurs mélanges, leurs sels acceptables sur le plan cosmétique ou pharmaceutique et/ou leurs variants fonctionnellement équivalents, des procédés de préparation, des compositions cosmétiques ou pharmaceutiques qui les contiennent et leur utilisation en médecine, particulièrement dans le traitement et/ou la prévention de la douleur, de l'inflammation, des démangeaisons, de maladies et/ou troubles neurologiques, compulsifs et/ou neuropsychiatriques et dans des procédés de traitement et/ou de soin de la peau, des cheveux et/ou des membranes muqueuses médiés par l'exocytose neuronale.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)