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1. WO2013153192 - COMPOUNDS WHICH INHIBIT NEURONAL EXOCYTOSIS (III)

Publication Number WO/2013/153192
Publication Date 17.10.2013
International Application No. PCT/EP2013/057658
International Filing Date 12.04.2013
IPC
A61K 8/64 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
18characterised by the composition
30containing organic compounds
64Proteins; Peptides; Derivatives or degradation products thereof
C07K 7/06 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
7Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
04Linear peptides containing only normal peptide links
06having 5 to 11 amino acids
CPC
A61K 2800/43
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
2800Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
40Chemical, physico-chemical or functional or structural properties of particular ingredients
42Colour properties
43Pigments; Dyes
A61K 2800/48
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
2800Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
40Chemical, physico-chemical or functional or structural properties of particular ingredients
48Thickener, Thickening system
A61K 2800/51
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
2800Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
40Chemical, physico-chemical or functional or structural properties of particular ingredients
51Chelating agents
A61K 2800/52
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
2800Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
40Chemical, physico-chemical or functional or structural properties of particular ingredients
52Stabilizers
A61K 2800/522
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
2800Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
40Chemical, physico-chemical or functional or structural properties of particular ingredients
52Stabilizers
522Antioxidants; Radical scavengers
A61K 2800/524
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
2800Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
40Chemical, physico-chemical or functional or structural properties of particular ingredients
52Stabilizers
524Preservatives
Applicants
  • LUBRIZOL ADVANCED MATERIALS, INC. [US]/[US]
Inventors
  • FERRER MONTIEL, Antonio
  • FERNÁNDEZ BALLESTER, Gregorio
  • GARCÍA ANTÓN, José maría
  • CARREÑO SERRAÏMA, Cristina
  • ALMIÑANA DOMÉNECH, Núria
  • DELGADO GONZÁLEZ, Raquel
Agents
  • CARBONELL VALLÈS, Enric
Priority Data
12382146.413.04.2012EP
61/652,65529.05.2012US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) COMPOUNDS WHICH INHIBIT NEURONAL EXOCYTOSIS (III)
(FR) COMPOSÉS INHIBANT L'EXOCYTOSE NEURONALE (III)
Abstract
(EN)
Compounds of general formula (I): R1-Wn-Xm-AA1-AA2-AA3-AA4-AA5-AA6-AA7-AA8-AA9-Yp-Zq-R2 (I ) their stereoisomers, mixtures thereof and/or their cosmetically or pharmaceutically acceptable salts, preparation processes, cosmetic or pharmaceutical compositions which contain them and their use in medicine, particularly in the treatment and/or prevention of pain, inflammation, itching, neurological, compulsive and/or neuropsychiatric diseases and/or disorders and in processes of treatment and/or care of the skin, hair and/or mucous membranes mediated by neuronal exocytosis.
(FR)
La présente invention concerne des composés de formule générale (I) : R1-Wn-Xm-AA1-AA2-AA3-AA4-AA5-AA6-AA7-AA8-AA9-Yp-Zq-R2 (I) leurs stéréoisomères, leurs mélanges et/ou leurs sels acceptables sur le plan cosmétique ou pharmaceutique, des procédés de préparation, des compositions cosmétiques ou pharmaceutiques qui les contiennent et leur utilisation en médecine, particulièrement dans le traitement et/ou la prévention de la douleur, de l'inflammation, des démangeaisons, de maladies et/ou troubles neurologiques, compulsifs et/ou neuropsychiatriques et dans des procédés de traitement et/ou de soin de la peau, des cheveux et/ou des membranes muqueuses médiés par l'exocytose neuronale.
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