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1. WO2013152265 - METHODS OF PRODUCING AND USING SILK MICROFIBERS

Publication Number WO/2013/152265
Publication Date 10.10.2013
International Application No. PCT/US2013/035389
International Filing Date 05.04.2013
IPC
D01C 3/00 2006.01
DTEXTILES; PAPER
01NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
CCHEMICAL OR BIOLOGICAL TREATMENT OF NATURAL FILAMENTARY OR FIBROUS MATERIAL TO OBTAIN FILAMENTS OR FIBRES FOR SPINNING; CARBONISING RAGS TO RECOVER ANIMAL FIBRES
3Treatment of animal material, e.g. chemical scouring of wool
D02J 1/00 2006.01
DTEXTILES; PAPER
02YARNS; MECHANICAL FINISHING OF YARNS OR ROPES; WARPING OR BEAMING
JFINISHING OR DRESSING OF FILAMENTS, YARNS, THREADS, CORDS, ROPES, OR THE LIKE
1Modifying the structure or properties resulting from a particular structure; Modifying, retaining, or restoring the physical form or cross-sectional shape, e.g. by use of dies or squeeze rollers
A61L 27/56 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
27Materials for prostheses or for coating prostheses
50Materials characterised by their function or physical properties
56Porous or cellular materials
CPC
A61L 2400/06
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
2400Materials characterised by their function or physical properties
06Flowable or injectable implant compositions
A61L 2430/02
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
2430Materials or treatment for tissue regeneration
02for reconstruction of bones; weight-bearing implants
A61L 27/3604
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
27Materials for ; grafts or; prostheses or for coating ; grafts or; prostheses
36containing ingredients of undetermined constitution or reaction products thereof ; , e.g. transplant tissue, natural bone, extracellular matrix
3604characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
A61L 27/365
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
27Materials for ; grafts or; prostheses or for coating ; grafts or; prostheses
36containing ingredients of undetermined constitution or reaction products thereof ; , e.g. transplant tissue, natural bone, extracellular matrix
3641characterised by the site of application in the body
3645Connective tissue
365Bones
A61L 27/3687
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
27Materials for ; grafts or; prostheses or for coating ; grafts or; prostheses
36containing ingredients of undetermined constitution or reaction products thereof ; , e.g. transplant tissue, natural bone, extracellular matrix
3683subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
3687characterised by the use of chemical agents in the treatment, e.g. specific enzymes, detergents, capping agents, crosslinkers, anticalcification agents
A61L 27/3821
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
27Materials for ; grafts or; prostheses or for coating ; grafts or; prostheses
36containing ingredients of undetermined constitution or reaction products thereof ; , e.g. transplant tissue, natural bone, extracellular matrix
38containing added animal cells
3804characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
3821Bone-forming cells, e.g. osteoblasts, osteocytes, osteoprogenitor cells
Applicants
  • TRUSTEES OF TUFTS COLLEGE [US]/[US]
Inventors
  • KAPLAN, David, L.
  • MANDAL, Biman B.
Agents
  • JARRELL, Brenda, Herschbach
Priority Data
61/621,20906.04.2012US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) METHODS OF PRODUCING AND USING SILK MICROFIBERS
(FR) PROCÉDÉS DE PRODUCTION ET D'UTILISATION DE MICROFIBRES DE SOIE
Abstract
(EN)
Provided herein relates to methods for preparing micron range silk fibers (or silk microfibers) and compositions comprising a micron range silk fiber (or a silk microfiber). The micron range silk fibers (or silk microfibers) can be used in various applications ranging from fillers in cosmetics to reinforcement materials to design high strength composites, e.g., reinforced scaffolds. In some embodiments, the silk microfiber-reinforced scaffolds can be used for bone graft applications because of their high compressive strength.
(FR)
La présente invention concerne des procédés de préparation de fibres de soie de l'ordre du micron (ou microfibres de soie) et des compositions comprenant une fibre de soie de l'ordre du micron (ou microfibre de soie). Les fibres de soie de l'ordre du micron (ou microfibres de soie) selon l'invention peuvent être utilisées dans différentes applications allant de charges cosmétiques à des matériaux de renforcement pour la conception de composites à haute résistance, par exemple, des supports renforcés. Dans certains modes de réalisation, lesdits supports renforcés par microfibres de soie peuvent être utilisés pour des applications de greffe osseuse du fait de leur haute résistance à la compression.
Also published as
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