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1. WO2013151440 - METHOD FOR DETERMINING TOXICITY

Publication Number WO/2013/151440
Publication Date 10.10.2013
International Application No. PCT/NL2013/050256
International Filing Date 05.04.2013
IPC
C12Q 1/68 2006.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
68involving nucleic acids
CPC
C12Q 1/689
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms
68involving nucleic acids
6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
6888for detection or identification of organisms
689for bacteria
C12Q 2600/142
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
2600Oligonucleotides characterized by their use
142Toxicological screening, e.g. expression profiles which identify toxicity
C12Q 2600/158
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
2600Oligonucleotides characterized by their use
158Expression markers
Applicants
  • STICHTING VU-VUMC [NL]/[NL]
Inventors
  • VAN STRAALEN, Nicolaas, Maria
  • ROELOFS, Theodorus, Frank, Maria
Agents
  • KREBS, Achim
Priority Data
200860805.04.2012NL
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) METHOD FOR DETERMINING TOXICITY
(FR) PROCÉDÉ DE DÉTERMINATION D'UNE TOXICITÉ
Abstract
(EN)
A method for determining toxicity of a sample, particularly a soil sample suspected of containing polycyclic aromatic hydrocarbon pollutants, is provided. The method allows for quantification of toxicity levels based on gene expression profiling of a test organism, for example Folsomia candida,exposed to the sample.
(FR)
La présente invention concerne un procédé permettant de déterminer la toxicité d'un échantillon, en particulier un échantillon de sol suspecté de contenir des polluants de type hydrocarbure aromatique polycyclique. Le procédé permet de quantifier des niveaux de toxicité sur la base du profilage de l'expression génétique d'un organisme testé, par exemple Folsomia candida, exposé à l'échantillon.
Also published as
Latest bibliographic data on file with the International Bureau