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1. WO2013150542 - A TRANSDERMAL PATCH FOR TREATMENT OF DEMENTIA OR ALZHEIMER TYPE DEMENTIA

Publication Number WO/2013/150542
Publication Date 10.10.2013
International Application No. PCT/IN2013/000163
International Filing Date 18.03.2013
IPC
A61P 25/28 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25Drugs for disorders of the nervous system
28for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
CPC
A61K 31/27
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
21Esters, e.g. nitroglycerine, selenocyanates
27of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
A61K 47/10
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
08containing oxygen, ; e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
A61K 9/70
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
70Web, sheet or filament bases ; ; Films; Fibres of the matrix type containing drug;
A61K 9/7053
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
70Web, sheet or filament bases ; ; Films; Fibres of the matrix type containing drug;
7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
703characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
7038Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
7046the adhesive comprising macromolecular compounds
7053obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
Applicants
  • SPARSHA PHARMA INTERNATIONAL PRIVATE LIMITED [IN]/[IN]
  • KUZUMAKI, Noriyuki [JP]/[IN] (US)
Inventors
  • KUZUMAKI, Noriyuki
Agents
  • HASAN, Afzal
Priority Data
1383/CHE/201205.04.2012IN
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) A TRANSDERMAL PATCH FOR TREATMENT OF DEMENTIA OR ALZHEIMER TYPE DEMENTIA
(FR) TIMBRE TRANSDERMIQUE POUR LE TRAITEMENT DE LA DÉMENCE OU DE LA DÉMENCE DE TYPE ALZHEIMER
Abstract
(EN)
Disclosed is a transdermal patch for treatment of degenerative neurological disorders like dementia or Alzheimer type dementia. More particularly, the transdermal patch for treatment of neurodegenerative disorder comprises anadhesive monolayer which comprises Rivastigmine in free base form or its pharmaceutically acceptable salts,styrene block copolymer, a tackifier, and an anti-oxidant, and where in total styrene units are in an amount of 4% w/w or more of said adhesive monolayer.
(FR)
La présente invention concerne un timbre transdermique pour le traitement de troubles neurologiques dégénératifs tels que la démence ou la démence de type Alzheimer. Plus particulièrement, le timbre transdermique destiné au traitement de troubles neurodégénératifs comprend une monocouche adhésive qui comprend de la Rivastigmine sous la forme base libre ou ses sels pharmaceutiquement acceptables, un copolymère séquencé de styrène, un épaississant, et un antioxydant, les unités styrènes totales étant présentes en une quantité de 4 % p/p ou plus de ladite monocouche adhésive.
Also published as
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