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1. WO2013149086 - APTAMERS TO PDGF AND VEGF AND THEIR USE IN TREATING PDGF AND VEGF MEDIATED CONDITIONS

Publication Number WO/2013/149086
Publication Date 03.10.2013
International Application No. PCT/US2013/034493
International Filing Date 28.03.2013
IPC
C12Q 1/68 2006.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
68involving nucleic acids
CPC
A61P 11/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
11Drugs for disorders of the respiratory system
A61P 13/12
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
13Drugs for disorders of the urinary system
12of the kidneys
A61P 19/04
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
19Drugs for skeletal disorders
04for non-specific disorders of the connective tissue
A61P 27/02
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
27Drugs for disorders of the senses
02Ophthalmic agents
A61P 27/04
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
27Drugs for disorders of the senses
02Ophthalmic agents
04Artificial tears; Irrigation solutions
A61P 27/06
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
27Drugs for disorders of the senses
02Ophthalmic agents
06Antiglaucoma agents or miotics
Applicants
  • SOMALOGIC, INC. [US]/[US]
Inventors
  • JARVIS, Thale C.
  • ROHLOFF, John C.
  • GELINAS, Amy D.
  • ZHANG, Chi
  • DROLET, Daniel W.
  • WAUGH, Sheela M.
  • JANJIC, Nebojsa
Agents
  • SWANSON & BRATSCHUN, L.L.C.
Priority Data
61/616,88128.03.2012US
61/648,39417.05.2012US
61/719,35426.10.2012US
61/722,09902.11.2012US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) APTAMERS TO PDGF AND VEGF AND THEIR USE IN TREATING PDGF AND VEGF MEDIATED CONDITIONS
(FR) APTAMÈRES DIRIGÉS CONTRE PDGF ET VEGF ET LEUR UTILISATION DANS LE TRAITEMENT D'ÉTATS À MÉDIATION PAR PDGF ET VEGF
Abstract
(EN)
Aptamers that bind PDGF and aptamers that bind VEGF are provided. In addition, aptamer constructs comprising a PDGF aptamer and a VEGF aptamer are provided. Pharmaceutical compositions comprising the aptamers and aptamer constructs are provided, as well as methods of treating conditions using the aptamers and aptamer constructs.
(FR)
L'invention concerne des aptamères qui se lient à PDGF et des aptamères qui se lient à VEGF. De plus, l'invention concerne des constructions d'aptamères comprenant un aptamère de PDGF et un aptamère de VEGF. L'invention concerne des composés pharmaceutiques comprenant les aptamères et des constructions d'aptamères, ainsi que des méthodes de traitement d'états à l'aide des aptamères et des constructions d'aptamères.
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