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Machine translation
1. (WO2013149075) COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING DISEASES ASSOCIATED WITH OXIDATIVE STRESS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2013/149075    International Application No.:    PCT/US2013/034467
Publication Date: 03.10.2013 International Filing Date: 28.03.2013
IPC:
A61K 33/36 (2006.01), A61K 33/18 (2006.01), A61K 33/14 (2006.01), A61K 9/08 (2006.01), A61K 9/14 (2006.01), A61P 17/14 (2006.01), A61P 17/00 (2006.01), A61K 9/06 (2006.01)
Applicants: CXL OPHTHALMICS, LLC [US/US]; 4354 Manchester Avenue Encinitas, CA 92024 (US)
Inventors: RUBINFELD, Roy, S.; (US).
HARTMAN, Raymond, A.; (US).
FELDMAN, Sandy, T.; (US)
Agent: PROCOPIO, CORY, HARGREAVES & SAVITCH LLP; 525 B Street. Suit 2200 San Diego, CA 82101 (US)
Priority Data:
61/617,501 29.03.2012 US
Title (EN) COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING DISEASES ASSOCIATED WITH OXIDATIVE STRESS
(FR) COMPOSITIONS ET PROCÉDÉS DE TRAITEMENT OU DE PRÉVENTION DE MALADIES ASSOCIÉES AU STRESS OXYDATIF
Abstract: front page image
(EN)Methods and compositions for treating various indications by lessening oxidative stress in a patient are provided. A pharmaceutical composition comprises between about 0.001% to about 10.0%), or more specifically between about 0.015% to about 5%, sodium iodine or catalase by weight. The iodine ion or the catalase dissociates hydrogen peroxide into water and molecular oxygen to interrupt biological events that result in negative side effects. The pharmaceutical composition further comprises in some cases a reducing agent or various carrier materials. The pharmaceutical composition is in some cases formulated for a variety of delivery methods.
(FR)L'invention concerne des procédés et des compositions pour traiter diverses indications en réduisant le stress oxydatif chez un patient. Une composition pharmaceutique comprend entre environ 0,001 % à environ 10,0 % ou, de manière plus spécifique, entre environ 0,015 % à environ 5 % d'iode de sodium ou de catalase en poids. L'ion d'iode ou la catalase dissocie le peroxyde d'hydrogène dans l'eau et l'oxygène moléculaire pour interrompre des évènements biologiques qui conduisent à des effets secondaires néfastes. La composition pharmaceutique comprend en outre dans certains cas un agent réducteur ou divers matériaux porteurs. La composition pharmaceutique est dans certains cas formulée pour une diversité de procédés d'administration.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)