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1. (WO2013148370) S100A8/A9 AS A DIAGNOSTIC MARKER AND A THERAPEUTIC TARGET
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2013/148370    International Application No.:    PCT/US2013/032617
Publication Date: 03.10.2013 International Filing Date: 15.03.2013
IPC:
G01N 33/574 (2006.01), G01N 33/68 (2006.01), G01N 33/48 (2006.01)
Applicants: SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH [US/US]; 1275 York Avenue New York, New York 10065 (US)
Inventors: MASSAGUE, Joan; (US).
ACHARYYA, Swarnali; (US)
Agent: LARSON, Marina, T.; Larson & Anderson, LLC P.O. Box 4928 Dillon, Colorado 80435 (US)
Priority Data:
61/618,357 30.03.2012 US
Title (EN) S100A8/A9 AS A DIAGNOSTIC MARKER AND A THERAPEUTIC TARGET
(FR) S100A8/A9 À TITRE DE MARQUEUR DIAGNOSTIQUE ET DE CIBLE THÉRAPEUTIQUE
Abstract: front page image
(EN)Determinations of the level of expression of S100A8/A9 protein serve as a prognostic indicator of the therapeutic response to a given type of chemotherapy treatment and as a monitoring indicator of the effectiveness of an on-going chemotherapy treatment for the treatment of breast cancer in human patients. Kits can be used for performing these determinations.
(FR)Selon la présente invention, les déterminations du niveau d'expression de la protéine S100A8/A9 servent d'indicateur pronostique de la réaction thérapeutique à un type donné de traitement chimiothérapique et d'indicateur de surveillance de l'efficacité d'un traitement chimiothérapique en cours pour le traitement du sein chez des patientes humaines. Des kits peuvent être utilisés pour effectuer de ces déterminations.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)