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1. (WO2013148284) ANTIBODIES THAT BIND TO A PCSK9 CLEAVAGE SITE AND METHODS OF USE

Pub. No.:    WO/2013/148284    International Application No.:    PCT/US2013/031722
Publication Date: Fri Oct 04 01:59:59 CEST 2013 International Filing Date: Fri Mar 15 00:59:59 CET 2013
IPC: C07K 16/40
A61K 39/395
C12N 15/13
Applicants: GENENTECH, INC.
F. HOFFMANN-LA ROCHE AG
Inventors: SAI, Tao
LAI, Joyce
KIRCHHOFER, Daniel
PETERSON, Andrew
LIPARI, Michael Terry
LI, Wei
IZRAEL-TOMASEVIC, Anita
ARNOTT, David
Title: ANTIBODIES THAT BIND TO A PCSK9 CLEAVAGE SITE AND METHODS OF USE
Abstract:
The invention provides anti-PCSK9 antibodies that bind to a PCSK9 cleavage site and methods of using the same.