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1. (WO2013148219) ANTI-METATSTATIC AGENTS PREDICATED UPON POLYAMINE-MACROCYCLIC CONJUGATES

Pub. No.:    WO/2013/148219    International Application No.:    PCT/US2013/031073
Publication Date: Fri Oct 04 01:59:59 CEST 2013 International Filing Date: Thu Mar 14 00:59:59 CET 2013
IPC: C07C 211/36
A61K 31/132
A61P 35/00
Applicants: UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC.
PHANSTIEL IV, Otto
MUTH, Aaron
Inventors: PHANSTIEL IV, Otto
MUTH, Aaron
Title: ANTI-METATSTATIC AGENTS PREDICATED UPON POLYAMINE-MACROCYCLIC CONJUGATES
Abstract:
Disclosed herein are novel motuporamine compounds that act as anti-metastatic agents with low toxicity and high anti-migration activity. The non-toxic, anti-metastatic agents may be given to patients with potential or actual metastatic cancers, such as pancreatic cancers, alone in combination with known and/or new therapies to help block the growth and spread of tumor(s)..