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1. (WO2013148189) PROBE INCORPORATION MEDIATED BY ENZYMES

Pub. No.:    WO/2013/148189    International Application No.:    PCT/US2013/030774
Publication Date: Fri Oct 04 01:59:59 CEST 2013 International Filing Date: Thu Mar 14 00:59:59 CET 2013
IPC: G01N 33/566
Applicants: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
Inventors: TING, Alice, Y.
LIU, Daniel, Shao-chen
Title: PROBE INCORPORATION MEDIATED BY ENZYMES
Abstract:
Compositions (e.g., lipoic acid ligase polypeptides and lipoic acid analogs) and uses thereof in the Probe Incorporation Mediated By Enzymes (PRIME) methods both in vitro and in vivo. Also described herein are kits for performing the PRIME method and vectors/kits for expressing the lipoic acid ligases.