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1. (WO2013148189) PROBE INCORPORATION MEDIATED BY ENZYMES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2013/148189    International Application No.:    PCT/US2013/030774
Publication Date: 03.10.2013 International Filing Date: 13.03.2013
IPC:
G01N 33/566 (2006.01)
Applicants: MASSACHUSETTS INSTITUTE OF TECHNOLOGY [US/US]; 77 Massachusetts Avenue Cambridge, MA 02139 (US)
Inventors: TING, Alice, Y.; (US).
LIU, Daniel, Shao-chen; (US)
Agent: CHEN, Yahua; Wolf, Greenfield & Sacks, P.C. 600 Atlantic Avenue Boston, MA 02210-2206 (US)
Priority Data:
61/617,808 30.03.2012 US
Title (EN) PROBE INCORPORATION MEDIATED BY ENZYMES
(FR) INCORPORATION DE SONDE À MÉDIATION PAR DES ENZYMES
Abstract: front page image
(EN)Compositions (e.g., lipoic acid ligase polypeptides and lipoic acid analogs) and uses thereof in the Probe Incorporation Mediated By Enzymes (PRIME) methods both in vitro and in vivo. Also described herein are kits for performing the PRIME method and vectors/kits for expressing the lipoic acid ligases.
(FR)L'invention concerne des compositions (par exemple, des polypeptides acide lipoïque ligases et des analogues d'acide lipoïque) et leurs utilisations dans des procédés d'Incorporation de Sonde à médiation par des Enzymes (PRIME) à la fois in vitro et in vivo. La présente invention concerne également des trousses pour la mise en œuvre du procédé PRIME et des vecteurs/trousses pour l'expression des acide lipoïque ligases.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)