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1. (WO2013148136) OMEGA-3 FATTY ACID ESTER COMPOSITIONS
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2013/148136 International Application No.: PCT/US2013/030211
Publication Date: 03.10.2013 International Filing Date: 11.03.2013
IPC:
A61K 31/05 (2006.01) ,A61K 31/232 (2006.01) ,A61K 31/7024 (2006.01) ,A61P 9/00 (2006.01) ,A61P 9/14 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
045
Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
05
Phenols
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
21
Esters, e.g. nitroglycerine, selenocyanates
215
of carboxylic acids
22
of acyclic acids, e.g. pravastatin
23
of acids having a carboxyl group bound to a chain of seven or more carbon atoms
232
having three or more double bonds, e.g. etretinate
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
70
Carbohydrates; Sugars; Derivatives thereof
7024
Esters of saccharides
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
9
Drugs for disorders of the cardiovascular system
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
9
Drugs for disorders of the cardiovascular system
14
Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
Applicants: SANCILIO & COMPANY, INC.[US/US]; 3874 Fiscal Court, Ste 200 Riviera Beach, Florida 33404-1785, US
Inventors: SANCILIO, Frederick; US
PERSICANER, Peter; US
CACACE, Janice; US
DAHIM, Mohand; US
Agent: MILLS, E., Eric; Ward and Smith, P. A. Wade II, Suite 400 5430 Wade Park Boulevard Post Office Box 33009 Raleigh, North Carolina 27636-3009, US
Priority Data:
61/618,16130.03.2012US
Title (EN) OMEGA-3 FATTY ACID ESTER COMPOSITIONS
(FR) COMPOSITIONS D'ESTER D'ACIDE GRAS OMÉGA-3
Abstract:
(EN) Described herein are compositions comprising at least one Omega-3 fatty acid ester and at least one surface active agent; wherein the compositions form micelles when in contact with an aqueous medium. Also provided is a method of administering to a subject a composition comprising at least one Omega-3 fatty acid ester and at least one surface active agent, wherein the at least one Omega-3 fatty acid ester forms micelles when in contact with an aqueous medium, and the bioavailability of the at least one Omega-3 fatty acid ester is substantially independent of a food effect. Said compositions are useful for treating cardiovascular conditions or disorders in a subject and for reducing side effects associated with the ingestion of Omega-3 fatty acid esters. Described are also various dosage forms for administering said compositions and use of said compositions in functional foods. Provided herein are also kits with instructions on how to administer said compositions.
(FR) La présente invention porte sur des compositions comprenant au moins un ester d'acide gras oméga-3 et au moins un agent tensioactif, les compositions formant des micelles lorsqu'elles sont en contact avec un milieu aqueux. L'invention porte également sur un procédé d'administration à un sujet d'une composition comprenant au moins un ester d'acide gras oméga-3 et au moins un agent tensioactif, ledit ou lesdits esters d'acides gras oméga-3 formant des micelles lorsqu'ils sont en contact avec un milieu aqueux et la biodisponibilité dudit ou desdits esters d'acides gras oméga-3 étant essentiellement indépendante d'un effet d'absorption d'aliment. Lesdites compositions sont utiles pour le traitement d'affections ou troubles cardiovasculaires chez un sujet et pour la réduction d'effets secondaires associés à l'ingestion d'esters d'acides gras oméga-3. La présente invention porte également sur diverses formes pharmaceutiques pour l'administration desdites compositions et sur l'utilisation desdites compositions dans des aliments fonctionnels. La présente invention porte également sur des trousses renfermant des instructions sur la manière d'administrer lesdites compositions.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)