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1. (WO2013147568) AMINOSTYRYLBENZOFURAN DERIVATIVES AS INHIBITORS AGAINST BETA-AMYLOID FIBRIL FORMATION, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2013/147568    International Application No.:    PCT/KR2013/002699
Publication Date: 03.10.2013 International Filing Date: 01.04.2013
IPC:
C07D 413/12 (2006.01), C07D 307/86 (2006.01), A61K 31/421 (2006.01), A61P 25/00 (2006.01)
Applicants: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY [KR/KR]; #39-1, Hawolgok-2-dong, Seongbuk-gu, Seoul 136-791 (KR)
Inventors: KIM, Dong Jin; (KR).
YOO, Kyung Ho; (KR).
KIM, Young Soo; (KR).
PARK, Woong Seo; (KR).
KANG, Yong Koo; (KR).
KIM, Hye Yun; (KR).
KIM, Yun Kyung; (KR).
PARK, Ki Duk; (KR).
KIM, Maeng Sup; (KR).
SUH, Kwee Hyun; (KR).
AHN, Young Gil; (KR)
Agent: FIRSTLAW P.C.; Trust Tower, 275-7 Yangjae-Dong, Seocho-Ku, Seoul 137-739 (KR)
Priority Data:
10-2012-0033590 30.03.2012 KR
Title (EN) AMINOSTYRYLBENZOFURAN DERIVATIVES AS INHIBITORS AGAINST BETA-AMYLOID FIBRIL FORMATION, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME
(FR) DÉRIVÉS AMINOSTYRYLBENZOFURANES EN TANT QU'INHIBITEURS DE LA FORMATION DE FIBRILLES DE BÊTA-AMYLOÏDE, ET COMPOSITION PHARMACEUTIQUE LES CONTENANT
Abstract: front page image
(EN)The present invention provides an aminostyrylbenzofuran compound of Formula (I), and a pharmaceutical composition comprising same. The pharmaceutical composition of the present invention comprising the compound of Formula (I), a pharmaceutically acceptable salt, an isomer, a hydrate, and a solvate thereof as an active ingredient can be useful for the prevention and treatment of degenerative brain diseases caused by accumulation of beta-amyloid.
(FR)La présente invention concerne un composé aminostyrylbenzofurane de formule (I), et une composition pharmaceutique le contenant. La composition pharmaceutique de la présente invention contenant le composé de formule (I), un sel pharmaceutiquement acceptable, un isomère, un hydrate et un solvate de celui-ci en tant que principe actif peut être utile pour la prévention et le traitement de maladies cérébrales dégénératives causées par l'accumulation de bêta-amyloïde.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)