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1. (WO2013147153) ANTI-LAMP5 ANTIBODY AND UTILIZATION THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2013/147153 International Application No.: PCT/JP2013/059516
Publication Date: 03.10.2013 International Filing Date: 29.03.2013
IPC:
C12N 15/09 (2006.01) ,A61K 39/395 (2006.01) ,A61P 35/00 (2006.01) ,C07K 19/00 (2006.01) ,C12N 1/15 (2006.01) ,C12N 1/19 (2006.01) ,C12N 1/21 (2006.01) ,C12N 5/10 (2006.01) ,C12P 21/08 (2006.01)
Applicants: CHUGAI SEIYAKU KABUSHIKI KAISHA[JP/JP]; 5-1, Ukima 5-chome, Kita-ku, Tokyo 1158543, JP
Inventors: KAWAI Shigeto; JP
Agent: CENTCREST IP ATTORNEYS; Kimpodo Bldg. 9th Floor, 2-8-21, Kyobashi, Chuo-ku, Tokyo 1040031, JP
Priority Data:
2012-07673529.03.2012JP
Title (EN) ANTI-LAMP5 ANTIBODY AND UTILIZATION THEREOF
(FR) ANTICORPS ANTI-LAMP5 ET SON UTILISATION
(JA) 抗LAMP5抗体およびその利用
Abstract: front page image
(EN) A monoclonal antibody recognizing the extracellular region of LAMP5. This antibody exhibits, on a multiple myeloma cell line, an antibody-dependent cell-mediated cytotoxic activity and/or a cell proliferation depressing activity in the presence of a toxin-labeled secondary antibody.
(FR) La présente invention concerne un anticorps monoclonal reconnaissant la région extracellulaire de LAMP5. Cet anticorps présente, sur une lignée cellulaire de myélome multiple, une activité cytotoxique à médiation cellulaire dépendante d'anticorps et/ou une activité de diminution de la prolifération cellulaire en présence d'un anticorps secondaire marqué avec une toxine.
(JA)  LAMP5の細胞外領域を認識するモノクローナル抗体を作製した。作製した抗体は、多発性骨髄腫細胞株に対して抗体依存性細胞介在性細胞傷害活性および/またはトキシン標識二次抗体存在下で細胞増殖抑制活性を示した。
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)