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1. (WO2013146943) ANTI-AGING AGENT CONTAINING ARCTIGENIN DERIVATIVE
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2013/146943 International Application No.: PCT/JP2013/059128
Publication Date: 03.10.2013 International Filing Date: 27.03.2013
IPC:
A61K 8/49 (2006.01) ,A61K 31/365 (2006.01) ,A61P 17/00 (2006.01) ,A61P 29/00 (2006.01) ,A61P 43/00 (2006.01) ,A61Q 19/02 (2006.01) ,A61Q 19/08 (2006.01) ,C07D 307/33 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8
Cosmetics or similar toilet preparations
18
characterised by the composition
30
containing organic compounds
49
containing heterocyclic compounds
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
335
having oxygen as the only ring hetero atom, e.g. fungichromin
365
Lactones
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
17
Drugs for dermatological disorders
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
29
Non-central analgesic, antipyretic or antiinflammatory agents, e.g antirheumatic agents; Non-steroidal antiinflammatory drugs (NSAIDs)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
43
Drugs for specific purposes, not provided for in groups A61P1/-A61P41/108
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
Q
SPECIFIC USE OF COSMETICS OR SIMILAR TOILET PREPARATIONS
19
Preparations for care of the skin
02
for chemically bleaching or whitening the skin
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
Q
SPECIFIC USE OF COSMETICS OR SIMILAR TOILET PREPARATIONS
19
Preparations for care of the skin
08
Anti-ageing preparations
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
307
Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
02
not condensed with other rings
26
having one double bond between ring members or between a ring member and a non-ring member
30
with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
32
Oxygen atoms
33
in position 2, the oxygen atom being in its keto or unsubstituted enol form
Applicants: ROHTO PHARMACEUTICAL CO., LTD.[JP/JP]; 1-8-1,Tatsumi-nishi,Ikuno-ku,Osaka-shi Osaka 5448666, JP
Inventors: HAYASHI,Yuya; JP
MIZUTARE,Yoko; JP
Agent: UNIUS PATENT ATTORNEYS OFFICE; SHIN-OSAKA MT Bldg. 1, 13-9, Nishinakajima 5-chome, Yodogawa-ku, Osaka-shi, Osaka 5320011, JP
Priority Data:
2012-08117730.03.2012JP
Title (EN) ANTI-AGING AGENT CONTAINING ARCTIGENIN DERIVATIVE
(FR) AGENT ANTIVIEILLISSEMENT CONTENANT UN DÉRIVÉ D'ARCTIGÉNINE
(JA) アルクチゲニン誘導体を含む抗老化剤
Abstract:
(EN) An arctigenin derivative is created and used for anti-aging treatment, including in order to protect skin from the sun and to recover skin elasticity. A variety of fatty acid ester derivatives, alcohol ether derivatives and alkylated derivatives are created as the arctigenin derivatives. Agents for controlling ET-1 production, elastase inhibitors, and anti-inflammatory agents are prepared. Such arctigenin derivatives are particularly useful as an external agent for the skin, such as an anti-inflammatory external agent for the skin, a sunscreen external agent for the skin, or an external agent for the skin for recovering elasticity.
(FR) Cette invention concerne un dérivé d'arctigénine fabriqué et utilisé pour un traitement antivieillissement, notamment pour la protection contre les rayons du soleil et la restauration de l'élasticité de la peau. Différents dérivés d'esters d'acides gras, dérivés d'éthers d'alcools et dérivés alkylés sont fabriqués en tant que dérivés d'arctigénine. Des agents régulant la production d'ET-1, des inhibiteurs d'élastase et des anti-inflammatoires sont préparés. De tels dérivés d'arctigénine sont particulièrement utiles en tant qu'agents externes pour la peau, par exemple en tant qu'anti-inflammatoire externe pour la peau, agent de protection solaire externe pour la peau ou agent externe pour la restauration de l'élasticité de la peau.
(JA)  アルクチゲニン誘導体を作成し、美白、皮膚弾力性回復を始めとする皮膚の抗老化の用途に供すること。 アルクチゲニン誘導体として、各種脂肪酸エステル誘導体、アルコールとのエーテル誘導体、アルキル化誘導体を作成する。このようなアルクチゲニン誘導体を有効成分として含有するET-1産生抑制剤、エラスターゼ阻害剤、抗炎症剤を調製する。このようなアルクチゲニン誘導体は、特に皮膚外用剤として有用であり、抗炎症用皮膚外用剤、美白用皮膚外用剤、あるいは皮膚弾力性回復用皮膚外用剤に調製され、使用される。
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)