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1. (WO2013146932) NOVEL BENZYLIDENE AZOLIDINE DERIVATIVE OR SALT THEREOF

Pub. No.:    WO/2013/146932    International Application No.:    PCT/JP2013/059112
Publication Date: Fri Oct 04 01:59:59 CEST 2013 International Filing Date: Thu Mar 28 00:59:59 CET 2013
IPC: C07D 233/96
A61K 8/49
A61Q 17/04
A61Q 19/00
C09K 3/00
Applicants: ROHTO PHARMACEUTICAL CO., LTD.
ロート製薬株式会社
Inventors: SHIMIZU,Takashi
清水 崇
Title: NOVEL BENZYLIDENE AZOLIDINE DERIVATIVE OR SALT THEREOF
Abstract:
Provided is a novel compound which has excellent ultraviolet absorbing function (especially UVA absorbing function) and excellent hydrophilicity. A benzylidene azolidine derivative of the present invention or a salt thereof is characterized by being a benzylidene azolidine derivative represented by specific structural formula (I) or a salt thereof. (In structural formula (I), n represents an integer of 1-5; A1 represents O, S or N-A4; and each of A2, A3 and A4 independently represents a hydrogen atom, an alkyl group which may be substituted by a hydroxyl group and has 1-8 carbon atoms, or the like (provided that at least one of A2, A3 and A4 contains one or more hydroxyl groups). In this connection, when n is an integer of 2-5, the plurality of A3O- moieties may be the same as or different from each other.)