JP2012002129 NEURONAL CULTURE MEDIUM AND METHOD FOR PRODUCING IN VIVO-LIKE AND ENHANCED SYNAPTOGENESIS NEURON MODEL

1. (WO2013144999) NEURONAL CULTURE MEDIUM AND METHOD FOR PRODUCING IN VIVO-LIKE AND ENHANCED SYNAPTOGENESIS NEURON MODEL

↓

Latest bibliographic data on file with the International Bureau

Pub. No.:	WO/2013/144999	International Application No.:	PCT/JP2012/002129
Publication Date:	03.10.2013	International Filing Date:	27.03.2012
Chapter 2 Demand Filed:	20.11.2012

IPC:

C12N 1/00 (2006.01), C12N 5/0793 (2010.01)

Applicants:

OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY GRADUATE UNIVERSITY [JP/JP]; 1919-1, Aza Tancha, Onna-son, Kunigami-gun, Okinawa 9040495 (JP) (For All Designated States Except US).
DIMITROV, Dimitar Ivanov [BG/JP]; (JP) (For US Only).
GUILLAUD, Laurent Elie [FR/JP]; (JP) (For US Only).
TAOUFIQ, Zacharie Mehdi Francois [FR/JP]; (JP) (For US Only).
TAKAHASHI, Tomoyuki [JP/JP]; (JP) (For US Only)

Inventors:

DIMITROV, Dimitar Ivanov; (JP).
GUILLAUD, Laurent Elie; (JP).
TAOUFIQ, Zacharie Mehdi Francois; (JP).
TAKAHASHI, Tomoyuki; (JP)

Agent:

HIRAKI, Yusuke; Atago Green Hills MORI Tower 32F, 5-1, Atago 2-chome, Minato-ku, Tokyo 1056232 (JP)

Priority Data:

Title

(EN) NEURONAL CULTURE MEDIUM AND METHOD FOR PRODUCING IN VIVO-LIKE AND ENHANCED SYNAPTOGENESIS NEURON MODEL
(FR) MILIEU DE CULTURE NEURONAL ET PROCÉDÉ DE PRODUCTION D'UN MODÈLE DE NEURONE À SYNAPTOGÉNÈSE DE TYPE IN-VIVO ET AMÉLIORÉE

Abstract:

(EN)An object of the present invention is to develop and provide a method for producing a neuron model having reproduced in vivo properties by improving a cell culture medium composition and a cell culture medium composition necessary for the production of such neuron model. According to the present invention, cell culture is carried out in vitro using a medium for producing in vivo-like and enhanced synaptogenesis neuron model supplemented with a medium supplement for producing in vivo-like and enhanced synaptogenesis neuron model comprising any or any combination of NT-3, potassium or a salt thereof, and FGF2.
(FR)Un objet de la présente invention est de développer et de fournir un procédé de production d'un modèle de neurone ayant des propriétés reproduites in vivo dans la cellule par l'amélioration d'une composition du milieu de culture cellulaire et une composition de milieu de culture cellulaire nécessaire pour la production d'un tel modèle de neurone. Selon la présente invention, une culture cellulaire est effectuée in vitro à l'aide d'un milieu de production d'un modèle de neurone à synaptogénèse de type in-vivo et améliorée complété d'un supplément de milieu de production d'un modèle de neurone à synaptogénèse de type in-vivo et améliorée comprenant l'un quelconque ou une combinaison quelconque de NT-3, de potassium ou un sel de celui-ci, et du FGF2.

Designated States:

AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).

Publication Language:	English (EN)
Filing Language:	English (EN)

Default Search Form
Default Tab Search Form
Interface Language
Skins
Multiple Windows Interface
Tooltip Help
IPC Tooltip Help