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1. (WO2013143548) COMPOUNDS CAPABLE OF MODULATING/PRESERVING ENDOTHELIAL INTEGRITY FOR USE IN PREVENTION OR TREATMENT OF ACUTE TRAUMATIC COAGULOPATHY AND RESUSCITATED CARDIAC ARREST
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2013/143548    International Application No.:    PCT/DK2013/050090
Publication Date: 03.10.2013 International Filing Date: 26.03.2013
IPC:
G01N 33/58 (2006.01), G01N 33/68 (2006.01), A61K 31/519 (2006.01), A61K 31/52 (2006.01), A61K 31/557 (2006.01)
Applicants: RIGSHOSPITALET [DK/DK]; Blegdamsvej 9 DK-2100 Copenhagen Ø (DK)
Inventors: JOHANSSON, Pär; (SE).
OSTROWSKI, Sisse Rye; (DK)
Agent: HØIBERG A/S; St. Kongensgade 59 A DK-1264 Copenhagen K (DK)
Priority Data:
PA 2012 70163 30.03.2012 DK
Title (EN) COMPOUNDS CAPABLE OF MODULATING/PRESERVING ENDOTHELIAL INTEGRITY FOR USE IN PREVENTION OR TREATMENT OF ACUTE TRAUMATIC COAGULOPATHY AND RESUSCITATED CARDIAC ARREST
(FR) COMPOSÉS CAPABLES DE MODULER/PRÉSERVER L'INTÉGRITÉ ENDOTHÉLIALE ET ADAPTÉS POUR ÊTRE UTILISÉS DANS LA PRÉVENTION OU LE TRAITEMENT DE LA COAGULOPATHIE TRAUMATIQUE AIGUË ET LA RÉANIMATION APRÈS ARRÊT CARDIAQUE
Abstract: front page image
(EN)The present invention relates to novel uses of compounds that protect the endothelium, particularly prostacyclin and variants and derivatives thereof in the treatment or prevention of acute traumatic coagulopathy (ATC) and of patients resuscitating from cardiac arrest. The invention also relates to a method of identifying individuals at risk of developing ATC.
(FR)La présente invention concerne des applications nouvelles de composés qui protègent l'endothélium, notamment la prostacycline et ses variants et dérivés dans le traitement ou la prévention de la coagulopathie traumatique aiguë (ATC) et de patients réanimés après un arrêt cardiaque. L'invention concerne également un procédé pour identifier les individus présentant un risque de développer une ATC.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)