CN2013073516 HYDRATE OF CYCLOPEPTIDE COMPOUND AS WELL AS PREPARATION METHOD AND USE THEREOF

1. (WO2013143501) HYDRATE OF CYCLOPEPTIDE COMPOUND AS WELL AS PREPARATION METHOD AND USE THEREOF

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Latest bibliographic data on file with the International Bureau

Pub. No.:		WO/2013/143501		International Application No.:		PCT/CN2013/073516
Publication Date:		03.10.2013		International Filing Date:		29.03.2013

IPC:

C07K 7/56 (2006.01), A61K 38/12 (2006.01), A61P 31/10 (2006.01)

Applicants:

SHANGHAI TECHWELL BIOPHARMACEUTICAL CO., LTD [CN/CN]; No. 4258 Jindu Road, Minhang District Shanghai 201108 (CN)

Inventors:

LIU, Shidong; (CN).
ZHANG, Zhaoli; (CN).
WANG, Xiusheng; (CN).
ZHANG, Xiao; (CN).
TANG, Zhijun; (CN).
JI, Xiaoming; (CN)

Agent:

XU & PARTNERS, LLC.; Room No.106, Building No.1, Universal High-Tech Plaza 958 Zhen Bei Road, Putuo District Shanghai 200333 (CN)

Priority Data:

201210090377.1

30.03.2012

Title

(EN) HYDRATE OF CYCLOPEPTIDE COMPOUND AS WELL AS PREPARATION METHOD AND USE THEREOF
(FR) HYDRATE D'UN COMPOSÉ CYCLOPEPTIDIQUE, SON PROCÉDÉ DE PRÉPARATION ET SON UTILISATION
(ZH) 一种环肽类化合物的水合物及其制备方法和用途

Abstract:

(EN)Disclosed is a hydrate of a compound as shown in Formula I. In Formula I, R represents H or a cation capable of forming a pharmaceutically acceptable salt. The mass percentage of water in the hydrate is more than 8%. The hydrate has good stability. Moreover, disclosed are a preparation method and a use thereof.
(FR)La présente invention concerne un hydrate d'un composé de formule I. Dans la formule I, R représente H ou un cation capable de former un sel pharmaceutiquement acceptable. Le pourcentage en poids d'eau dans l'hydrate est supérieur à 8 %. Ledit hydrate présente une bonne stabilité. L'invention concerne, par ailleurs, un procédé de préparation dudit hydrate et son utilisation.
(ZH)本发明公开了式I所示化合物的水合物，其中，R表示H或者能形成药学上可接受的盐的阳离子，该水合物中水的质量百分含量大于8%，其具有良好稳定性。并且公开了它们的制备方法和用途。

Designated States:

AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).

Publication Language:	Chinese (ZH)
Filing Language:	Chinese (ZH)

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