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|1. (WO2013143259) PHOSPHODIESTERASE-4 INHIBITOR CAPABLE OF AVOIDING VOMIT REACTION AND PREPARATION METHOD FOR SAME|
|Title:||PHOSPHODIESTERASE-4 INHIBITOR CAPABLE OF AVOIDING VOMIT REACTION AND PREPARATION METHOD FOR SAME|
The present invention relates to a phosphodiesterase-4 inhibitor capable of avoiding a vomit reaction. The phosphodiesterase-4 inhibitor is a compound, a prodrug or a solvate represented by DTPM. The name of DTPM is 1-(4-difluoro methoxy-3-(tetrahydrofuran-3-oxyl)phenyl)-3-dimethyl-1-ketone, and a chemical formula is shown in formula (I). The compound in the present invention can prepare a drug that can effectively weaken or even avoid an adverse reaction such as vomit, can treat depression and alzheimer disease and can improve cognitive competence.