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1. WO2013135722 - METHOD FOR PREDICTING AWAKENING IN A COMATOSE PATIENT AND COMPUTER-IMPLEMENTED METHOD THEREOF

Publication Number WO/2013/135722
Publication Date 19.09.2013
International Application No. PCT/EP2013/055036
International Filing Date 12.03.2013
IPC
A61B 5/0484 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes; Identification of persons
04Measuring bioelectric signals of the body or parts thereof
0476Electroencephalography
0484using evoked response
A61B 5/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes; Identification of persons
CPC
A61B 2505/03
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
2505Evaluating, monitoring or diagnosing in the context of a particular type of medical care
03Intensive care
A61B 5/04012
A61B 5/0476
A61B 5/04845
A61B 5/38
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes
24Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
316Modalities, i.e. specific diagnostic methods
369Electroencephalography [EEG]
377using evoked responses
38Acoustic or auditory stimuli
A61B 5/4076
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes
40Detecting, measuring or recording for evaluating the nervous system
4076Diagnosing or monitoring particular conditions of the nervous system
Applicants
  • CENTRE HOSPITALIER UNIVERSITAIRE VAUDOIS (C.H.U.V.) [CH]/[CH]
Inventors
  • DE LUCIA, Marzia
  • TZOVARA, Athina
Agents
  • KATZAROV SA
Priority Data
61/609,44412.03.2012US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) METHOD FOR PREDICTING AWAKENING IN A COMATOSE PATIENT AND COMPUTER-IMPLEMENTED METHOD THEREOF
(FR) PROCÉDÉ DE PRÉDICTION DU RÉVEIL D'UN PATIENT COMATEUX ET SON PROCÉDÉ MIS EN ŒUVRE PAR ORDINATEUR
Abstract
(EN)
The present invention relates to a method for predicting awakening in a comatose patient based on the progression of auditory discrimination during early stages of coma. EEG measures are acquired from the patient during two distinct periods when said patient is exposed to auditory stimuli comprising repeated standard and deviant sounds. The first period occurs when the comatose patient is in a hypothermia state and the second period occurs when the comatose patient is in a normal temperature state and preferably within 2-3 days from the onset of the coma. The present invention further relates to a computer-implemented method thereof.
(FR)
La présente invention concerne un procédé pour prédire le réveil d'un patient comateux sur la base de l'évolution de la discrimination auditive pendant des stades précoces du coma. Des mesures EEG sont acquises à partir du patient pendant deux périodes distinctes lorsque ledit patient est exposé à des stimuli auditifs comprenant des sons standard et déviants répétés. La première période survient lorsque le patient comateux est dans un état d'hypothermie et la seconde période survient lorsque le patient comateux est dans un état de température normale et, de préférence, dans les 2 à 3 jours suivant le début du coma. La présente invention concerne en outre son procédé mis en œuvre par ordinateur.
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