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1. (WO2013126799) COMPOSITIONS AND METHODS FOR OCULAR DELIVERY OF A THERAPEUTIC AGENT

Pub. No.:    WO/2013/126799    International Application No.:    PCT/US2013/027465
Publication Date: Fri Aug 30 01:59:59 CEST 2013 International Filing Date: Sat Feb 23 00:59:59 CET 2013
IPC: A61K 47/42
A61K 45/00
A61K 9/14
A61K 9/52
A61K 9/64
A61K 31/00
A61K 31/192
A61K 31/56
A61K 31/395
A61K 31/16
A61M 31/00
A61M 5/00
A61P 27/02
A61F 9/00
G02C 7/04
A61F 2/00
B82B 1/00
B82B 3/00
Applicants: TRUSTEES OF TUFTS COLLEGE
Inventors: KAPLAN, David L.
LOVETT, Michael L.
WANG, Xiaoqin
YUCEL, Tuna
Title: COMPOSITIONS AND METHODS FOR OCULAR DELIVERY OF A THERAPEUTIC AGENT
Abstract:
Embodiments of various aspects described herein are directed to silk-based compositions for ocular delivery of at least one active agent, e.g., at least one therapeutic agent and methods of using the same. In some embodiments, the silk-based compositions can provide sustained release of at least one therapeutic agent to at least a portion of an eye. Thus, some embodiments of the silk-based compositions can be used for treatment of an ocular condition, e.g., age-related macular degeneration.