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1. (WO2013126746) DLL3 MODULATORS AND METHODS OF USE
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2013/126746 International Application No.: PCT/US2013/027391
Publication Date: 29.08.2013 International Filing Date: 22.02.2013
Chapter 2 Demand Filed: 20.12.2013
IPC:
C07K 16/28 (2006.01) ,A61K 47/48 (2006.01) ,C07K 16/30 (2006.01) ,C07K 14/47 (2006.01) ,A61P 35/00 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18
against material from animals or humans
28
against receptors, cell surface antigens or cell surface determinants
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
48
the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18
against material from animals or humans
28
against receptors, cell surface antigens or cell surface determinants
30
from tumour cells
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435
from animals; from humans
46
from vertebrates
47
from mammals
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35
Antineoplastic agents
Applicants: STEM CENTRX, INC.[US/US]; 450 East Jamie Court South San Francisco, CA 94080, US
Inventors: STULL, Robert, A.; US
SAUNDERS, Laura; US
DYLLA, Scott, J.; US
FOORD, Orit; US
LIU, David; US
TORGOV, Michael; US
SHAO, Hui; US
Agent: GARRETT, Arthur, S.; Finnegan, Henderson, Farabow, Garrett & Dunner, LLP 901 New York Avenue, NW Washington, DC 20001-4313, US
MEIGS, Julie, Broadus; Womble Carlyle Sandridge & Rice, LLP P.O. Box 7037 Atlanta, GA 30357-0037, US
Priority Data:
61/603,17324.02.2012US
61/719,80329.10.2012US
Title (EN) DLL3 MODULATORS AND METHODS OF USE
(FR) NOUVEAUX MODULATEURS ET LEURS PROCÉDÉS D'UTILISATION
Abstract:
(EN) Modulators of DLL3, including antibodies and derivatives thereof, and methods of using such modulators to treat proliferative disorders are provided.
(FR) L'invention concerne de nouveaux modulateurs, comprenant des anticorps et des dérivés de ceux-ci, et des procédés d'utilisation desdits modulateurs pour traiter des troubles prolifératifs.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)