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1. (WO2013126721) ENGINEERING MICROBES AND METABOLIC PATHWAYS FOR THE PRODUCTION OF ETHYLENE GLYCOL
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2013/126721 International Application No.: PCT/US2013/027351
Publication Date: 29.08.2013 International Filing Date: 22.02.2013
IPC:
C12P 7/18 (2006.01)
Applicants: MASSACHUSETTS INSTITUTE OF TECHNOLOGY[US/US]; 77 Massachusetts Avenue Cambridge, MA 02139, US
Inventors: STEPHANOPOULOS, Gregory; US
PEREIRA, Brian; US
DE MEY, Marjan; BE
DUGAR, Deepak; US
AVALOS, Jose, Luis; US
Agent: VAN AMSTERDAM, John, R.; Wolf, Greenfield & Sacks, P.C. 600 Atlantic Avenue Boston, MA 02210-2206, US
Priority Data:
61/602,32223.02.2012US
Title (EN) ENGINEERING MICROBES AND METABOLIC PATHWAYS FOR THE PRODUCTION OF ETHYLENE GLYCOL
(FR) MANIPULATION DE MICROBES ET VOIES MÉTABOLIQUES POUR LA PRODUCTION D'ÉTHYLÈNEGLYCOL
Abstract: front page image
(EN) The invention relates to recombinant cells and their use in the production of ethylene glycol. The cells in some embodiments have reduced or eliminated activity or expression of aldehyde dehydrogenase A relative to a wild type cell. In-some embodiments, the aldehyde dehydrogenase A is encoded by an aldA gene, and the cell includes a deletion of the aldA gene.
(FR) L'invention concerne des cellules recombinées et leur utilisation dans la production d'éthylèneglycol. Les cellules dans certaines formes de réalisation ont une activité ou une expression réduite ou éliminée de l'aldéhyde déshydrogénase A par rapport à une cellule de type sauvage. Dans certaines formes de réalisation, l'aldéhyde déshydrogénase A est codée par un gène aldA, et la cellule inclut une délétion du gène aldA.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)