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Machine translation
1. (WO2013126590) PHARMACEUTICAL COMPOSITION COMPRISING CD34+ CELLS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2013/126590    International Application No.:    PCT/US2013/027163
Publication Date: 29.08.2013 International Filing Date: 21.02.2013
IPC:
A61K 35/14 (2006.01), A61K 47/00 (2006.01), C12N 5/071 (2010.01), A61P 9/10 (2006.01), A61K 35/12 (2006.01)
Applicants: BAXTER INTERNATIONAL INC. [US/US]; One Baxter Parkway Deerfield, IL 60015 (US).
BAXTER HEALTHCARE S.A. [CH/CH]; Thurgauerstrasse 130 CH-8152 Glattpark (opfikon) (CH)
Inventors: MOTLAGH, Delara; (US).
COHEN, Amy; (US).
PALMER, Lora; (US).
AMRANI, David L.; (US)
Agent: HONG, Julie, J.; Marshall, Gerstein & Borun LLP 233 S. Wacker Drive 6300 Willis Tower Chicago, IL 60606-6357 (US)
Priority Data:
61/601,326 21.02.2012 US
Title (EN) PHARMACEUTICAL COMPOSITION COMPRISING CD34+ CELLS
(FR) COMPOSITION PHARMACEUTIQUE COMPORTANT DES CELLULES CD34+
Abstract: front page image
(EN)The invention relates to the field of treatment of ischemic conditions and diseases using a cell population comprising CD34+ cells isolated from peripheral blood of a subject. The invention provides a pharmaceutical composition comprising (i) a cell population comprising CD34+ cells, (ii) a plasma protein, and (iii) an isotonic solution comprising at least one salt, said isotonic solution comprising acetate, gluconate, or both acetate and gluconate. Methods of treating tissue damaged by ischemia in a subject and methods of treating a medical condition, wherein the pharmaceutical composition of the invention is administered, are further provided herein. Also, methods of promoting mobilization of CD34+ cells from bone marrow into peripheral blood are provided herein.
(FR)L'invention concerne le domaine du traitement d'états et de maladies ischémiques à l'aide d'une population cellulaire comportant des cellules CD34+ isolées dans le sang périphérique d'un sujet. L'invention concerne une composition pharmaceutique qui comporte (i) une population cellulaire comportant des cellules CD34+, (ii) une protéine de plasma, et (iii) une solution isotonique comportant au moins un sel, ladite solution isotonique comportant de l'acétate, du gluconate ou à la fois de l'acétate et du gluconate. L'invention concerne des méthodes de traitement d'un tissu endommagé par l'ischémie chez un sujet et des méthodes de traitement d'un état médical, la composition pharmaceutique de l'invention étant administrée. L'invention concerne également des procédés pour favoriser la mobilisation des cellules CD34+ dans la moelle osseuse vers le sang périphérique.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)