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1. (WO2013125687) THERAPEUTIC AGENT FOR INFLAMMATORY DISEASE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2013/125687    International Application No.:    PCT/JP2013/054551
Publication Date: 29.08.2013 International Filing Date: 22.02.2013
Chapter 2 Demand Filed:    31.07.2013    
IPC:
A61K 39/395 (2006.01), A61P 13/12 (2006.01), A61P 29/00 (2006.01), A61P 31/04 (2006.01), C07K 7/06 (2006.01), C07K 16/44 (2006.01), C12N 5/10 (2006.01), C12N 15/09 (2006.01)
Applicants: JOSAI UNIVERSITY CORPORATION [JP/JP]; 3-26, Kioi-cho, Chiyoda-ku, Tokyo 1020094 (JP)
Inventors: SATO Shuji; (JP).
GOTO Takeshi; (JP).
OHMORI Naoya; (JP).
CHIANG Kueichen; (JP).
SHIMADA Yayoi; (JP).
INOMATA Masafumi; (JP).
KUSANO Toru; (JP).
HIRATSUKA Takahiro; (JP).
NOGUCHI Takayuki; (JP).
HAGIWARA Satoshi; (JP)
Agent: KATSUNUMA Hirohito; Kyowa Patent & Law Office, Nippon Life Marunouchi Building, Marunouchi 1-6-6, Chiyoda-ku, Tokyo 1000005 (JP)
Priority Data:
2012-035965 22.02.2012 JP
Title (EN) THERAPEUTIC AGENT FOR INFLAMMATORY DISEASE
(FR) AGENT THÉRAPEUTIQUE POUR MALADIE INFLAMMATOIRE
(JA) 炎症疾患治療剤
Abstract: front page image
(EN)The present invention relates to a therapeutic agent for histone-induced inflammation, said therapeutic agent comprising a monoclonal antibody, or an antigen-binding fragment thereof, which can bind to a peptide comprising an amino acid sequence represented by SSVLYGGPPSAA (SEQ ID NO:1) or a conjugate of said peptide with a pharmaceutically acceptable carrier.
(FR)La présente invention concerne un agent thérapeutique pour inflammation provoquée par l'histone, ledit agent thérapeutique comprenant un anticorps monoclonal ou un fragment de liaison à l'antigène correspondant qui peut se lier à un peptide comprenant une séquence d'acides aminés représentée par SSVLYGGPPSAA (SEQ ID NO : 1) ou un conjugué dudit peptide avec un support pharmaceutiquement acceptable.
(JA) 本発明は、SSVLYGGPPSAA(配列番号1)で表わされるアミノ酸配列からなるペプチドまたは該ペプチドと薬学上許容可能な担体との結合体と結合する、モノクローナル抗体またはその抗原結合断片を含んでなる、ヒストンの関与する炎症治療剤に関する。
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)