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1. (WO2013124473) PILUS PROTEINS AND COMPOSITIONS

Pub. No.:    WO/2013/124473    International Application No.:    PCT/EP2013/053644
Publication Date: Fri Aug 30 01:59:59 CEST 2013 International Filing Date: Sun Feb 24 00:59:59 CET 2013
IPC: C07K 1/00
Applicants: NOVARTIS AG
Inventors: MAIONE, Domenico
COZZI, Roberta
RINAUDO, Cira Daniela
LAZZARIN, Maddalena
ZERBINI, Francesca
MARGARIT Y ROS, Immaculada
Title: PILUS PROTEINS AND COMPOSITIONS
Abstract:
The invention provides methods of forming pili in vitro and proteins suitable for use in these methods. The invention also provides pili produced by these methods and compositions comprising these pili for the treatment and prevention of bacterial disease, in particular of conditions caused by Streptococcus.