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1. (WO2013123463) A SYSTEM AND METHOD OF GENOMIC PROFILING
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2013/123463 International Application No.: PCT/US2013/026532
Publication Date: 22.08.2013 International Filing Date: 15.02.2013
IPC:
C12Q 1/68 (2006.01)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
Q
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1
Measuring or testing processes involving enzymes or micro-organisms; Compositions therefor; Processes of preparing such compositions
68
involving nucleic acids
Applicants: THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE[US/US]; 445 N. Fifth Street Suite 600 Phoenix, Arizona 85004, US
Inventors: BARRETT, Michael T.; US
LENKIEWICZ, Elizabeth; US
HOLLEY, Tara; US
Agent: FULLER, Rodney J.; Booth Udall Fuller, PLC 1255 West Rio Salado Parkway Suite 215 Tempe, Arizona 85281, US
Priority Data:
61/599,31715.02.2012US
Title (EN) A SYSTEM AND METHOD OF GENOMIC PROFILING
(FR) SYSTÈME ET PROCÉDÉ DE PROFILAGE GÉNOMIQUE
Abstract:
(EN) The present invention relates to a system and method of genomic profiling and is particularly useful in genomic differentiation of heterogeneous and polyclonal neoplastic cell populations, preferably of flow sorted formalin fixed paraffin embedded samples. The present invention includes methods of improving resolution for identifying aberration in variable carcinoma genomes and/or heterogeneous cell populations. The present invention also includes kits configured to improve genomic resolution and the ability to identify genomic aberration in variable and/or heterogeneous cell populations.
(FR) La présente invention concerne un système et un procédé de profilage génomique, et est particulièrement utile dans la différenciation génomique de populations de cellules néoplasiques hétérogènes et polyclonales, de préférence d'échantillons inclus dans la paraffine fixés à la formaline triés en flux. La présente invention comprend des procédés d'amélioration de la résolution pour identifier une aberration dans des génomes de carcinome variables et/ou des populations de cellules hétérogènes. La présente invention comprend également des kits conçus pour améliorer la résolution génomique et la capacité d'identifier une aberration génomique dans des populations de cellules variables et/ou hétérogènes.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)