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1. (WO2013123407) THERMOSENSITIVE NANOPARTICLE FORMULATIONS AND METHOD OF MAKING THE SAME

Pub. No.:    WO/2013/123407    International Application No.:    PCT/US2013/026453
Publication Date: Fri Aug 23 01:59:59 CEST 2013 International Filing Date: Sat Feb 16 00:59:59 CET 2013
IPC: A61K 9/127
Applicants: CELSION CORPORATION
Inventors: REED, Robert, A.
SU, Daishui
Title: THERMOSENSITIVE NANOPARTICLE FORMULATIONS AND METHOD OF MAKING THE SAME
Abstract:
The present invention relates to a formulation of thertnosensiiive liposomes, and more specifically to a formulation of liposomes comprising phospholipids and a surface active agent, wherein the liposomes support long term storage at temperatures less than or equal to about 8 °C, control degradate formation to maximize product potency and release their contents at mild hyperthermic temperatures. Methods of making formulations are also described.