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1. (WO2013123282) XENOANTIGEN-DISPLAYING ANTI-CANCER VACCINES AND METHOD OF MAKING

Pub. No.:    WO/2013/123282    International Application No.:    PCT/US2013/026271
Publication Date: Fri Aug 23 01:59:59 CEST 2013 International Filing Date: Sat Feb 16 00:59:59 CET 2013
IPC: A61K 47/44
Applicants: THE UNIVERSITY OF TOLEDO
SUCHECK, Steven, J.
WALL, Katherine, A.
SARKAR, Sourav
Inventors: SUCHECK, Steven, J.
WALL, Katherine, A.
SARKAR, Sourav
Title: XENOANTIGEN-DISPLAYING ANTI-CANCER VACCINES AND METHOD OF MAKING
Abstract:
Compositions, methods of making, and methods of using, xenoantigen-displaying anticancer vaccines are described. In another broad aspect, there is provided herein a method of synthesizing an alkynefunctionalized composition of claim 1, comprising: deprotecting an ester comprising a Fmoc moiety to form a free acid; coupling the free acid of step (a) with an amine; and, removing the Fmoc moiety, and coupling the remaining moiety with palmitic acid to yield an alkyne-functionalized composition.