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1. (WO2013123035) SYSTEM AND METHOD FOR PROCESSING AND DETECTING NUCLEIC ACIDS

Pub. No.:    WO/2013/123035    International Application No.:    PCT/US2013/025918
Publication Date: Fri Aug 23 01:59:59 CEST 2013 International Filing Date: Thu Feb 14 00:59:59 CET 2013
IPC: C12Q 1/68
Applicants: NEUMODX MOLECULAR, INC.
Inventors: WILLIAMS, Jeffrey
BRAHMASANDRA, Sundaresh
KUSNER, Michael, T.
Title: SYSTEM AND METHOD FOR PROCESSING AND DETECTING NUCLEIC ACIDS
Abstract:
A system and method for processing and detecting nucleic acids from a set of biological samples, comprising: a capture plate and a capture plate module configured to facilitate binding of nucleic acids within the set of biological samples to magnetic beads; a molecular diagnostic module configured to receive nucleic acids bound to magnetic beads, isolate nucleic acids, and analyze nucleic acids, comprising a cartridge receiving module, a heating/cooling subsystem and a magnet configured to facilitate isolation of nucleic acids, a valve actuation subsystem configured to control fluid flow through a microfluidic cartridge for processing nucleic acids, and an optical subsystem for analysis of nucleic acids; a fluid handling system configured to deliver samples and reagents to components of the system to facilitate molecular diagnostic protocols; and an assay strip configured to combine nucleic acid samples with molecular diagnostic reagents for analysis of nucleic acids.