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1. (WO2013122178) PHARMACEUTICAL COMPOSITION FOR CANCER TREATMENT INCLUDING FUSION PROTEIN
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2013/122178    International Application No.:    PCT/JP2013/053613
Publication Date: 22.08.2013 International Filing Date: 15.02.2013
Chapter 2 Demand Filed:    10.12.2013    
IPC:
A61K 38/00 (2006.01), A61K 35/12 (2006.01), A61K 38/16 (2006.01), A61K 39/00 (2006.01), A61P 9/00 (2006.01), A61P 11/00 (2006.01), A61P 13/00 (2006.01), A61P 25/00 (2006.01), A61P 31/00 (2006.01), A61P 35/00 (2006.01), A61P 37/00 (2006.01), C12N 5/077 (2010.01), C12N 5/078 (2010.01), C12N 15/09 (2006.01)
Applicants: NATIONAL UNIVERSITY CORPORATION OKAYAMA UNIVERSITY [JP/JP]; 1-1, Tsushima-Naka 1-chome, Kita-ku, Okayama-shi, Okayama 7008530 (JP) (JP only).
WATANABE Masami [JP/JP]; (JP) (AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BE, BF, BG, BH, BJ, BN, BR, BW, BY, BZ, CA, CF, CG, CH, CI, CL, CM, CN, CO, CR, CU, CY, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, FR, GA, GB, GD, GE, GH, GM, GN, GQ, GR, GT, GW, HN, HR, HU, ID, IE, IL, IN, IS, IT, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MC, MD, ME, MG, MK, ML, MN, MR, MT, MW, MX, MY, MZ, NA, NE, NG, NI, NL, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SI, SK, SL, SM, SN, ST, SV, SY, SZ, TD, TG, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW only)
Inventors: WATANABE Masami; (JP).
KUMON Hiromi; (JP).
NASU Yasutomo; (JP)
Agent: HIRAKI Yusuke; Atago Green Hills MORI Tower 32F, 5-1, Atago 2-chome, Minato-ku, Tokyo 1056232 (JP)
Priority Data:
2012-032073 16.02.2012 JP
2012-126467 01.06.2012 JP
Title (EN) PHARMACEUTICAL COMPOSITION FOR CANCER TREATMENT INCLUDING FUSION PROTEIN
(FR) COMPOSITION PHARMACEUTIQUE POUR LE TRAITEMENT DU CANCER COMPRENANT UNE PROTÉINE DE FUSION
(JA) 融合タンパク質を含む癌治療用医薬組成物
Abstract: front page image
(EN) The purpose of the present invention is to use a protein obtained by fusing a cancer-specific antigen and a cytokine as a prophylactic or therapeutic agent for cancer. A pharmaceutical composition for preventing or treating cancer, including, as an active ingredient, a protein obtained by fusing a cancer-specific antigen and a cytokine selected from the group consisting of human IL-2 (hIL2), human IL-4 (hIL4), human IL-7 (hIL7), human GMCSF (hGMCSF), mouse IL-4 (mIL4), and mouse GMCSF (mGMCSF).
(FR) La présente invention a pour objet l'utilisation d'une protéine obtenue par fusion d'un antigène spécifique du cancer et d'une cytokine en tant qu'agent prophylactique ou thérapeutique contre le cancer. L'invention concerne une composition pharmaceutique pour prévenir ou traiter le cancer, comprenant, en tant qu'ingrédient actif, une protéine obtenue par fusion d'un antigène spécifique du cancer et d'une cytokine sélectionnée dans le groupe constitué de l'IL-2 humaine (hIL2), l'IL-4 humaine (hIL4), l'IL-7 humaine (hIL7), le GMCSF humain (hGMCSF), l'IL-4 murine (mIL4), et le GMCSF murin (mGMCSF).
(JA) 本発明は、癌特異抗原とサイトカインの融合タンパク質を癌の予防又は治療剤として用いることを目的とする。 癌特異抗原とヒトIL2(hIL2)、ヒトIL4(hIL4)、ヒトIL7(hIL7)、ヒトGMCSF(hGMCSF)、マウスIL4(mIL4)及びマウスGMCSF(mGMCSF)からなる群から選択されるサイトカインとの融合タンパク質を有効成分として含む、癌の予防又は治療用医薬組成物。
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)