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1. (WO2013122072) METHOD AND DEVICE FOR MEASURING BLOOD INFORMATION

Pub. No.:    WO/2013/122072    International Application No.:    PCT/JP2013/053321
Publication Date: Fri Aug 23 01:59:59 CEST 2013 International Filing Date: Thu Feb 14 00:59:59 CET 2013
IPC: G01N 21/27
Applicants: NATIONAL UNIVERSITY CORPORATION TOKYO MEDICAL AND DENTAL UNIVERSITY
国立大学法人東京医科歯科大学
Inventors: SAKOTA, Daisuke
迫田 大輔
TAKATANI, Setsuo
高谷 節雄
Title: METHOD AND DEVICE FOR MEASURING BLOOD INFORMATION
Abstract:
First measurement light (30) is emitted to the interface between blood (10) that flows in a flow cell (40) formed using a transparent material having a different refractive index from that of plasma (a plasma layer) (12) in the blood (10) and the flow cell (40) from an oblique direction at an angle smaller than 90 degrees, then light (32) that is specularly reflected on the interface between the flow cell (40) and the blood (10) is dispersed to obtain absorption spectra, and then the information on a plasma component (a refractive index (Np) of plasma) is obtained from the absorption spectra. In this manner, only reflected light on the plasma layer can be extracted, only the information on the plasma component can be obtained continuously in a non-invasive manner without the need of separating blood components by a mechanical or chemical treatment and without relying on hematocrit, and therefore it becomes possible to obtain information on blood, such as hemolysis (the concentration of free plasma hemoglobin) and the degree of coagulation of blood (thrombi).