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1. WO2013121214 - REDUCTION OF GASTROINTESTINAL TRACT COLONISATION BY CAMPYLOBACTER

Publication Number WO/2013/121214
Publication Date 22.08.2013
International Application No. PCT/GB2013/050367
International Filing Date 15.02.2013
IPC
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
185
Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
19
Carboxylic acids, e.g. valproic acid
191
Acyclic acids having two or more hydroxy groups, e.g. gluconic acid
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
16
Amides, e.g. hydroxamic acids
164
of a carboxylic acid with an aminoalcohol, e.g. ceramides
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
33
Medicinal preparations containing inorganic active ingredients
24
Heavy metals; Compounds thereof
26
Iron; Compounds thereof
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
02
Bacterial antigens
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31
Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
04
Antibacterial agents
A61K 31/191 (2006.01)
A61K 31/164 (2006.01)
A61K 33/26 (2006.01)
A61K 39/02 (2006.01)
A61P 31/04 (2006.01)
CPC
A23K 20/111
A23K 20/142
A23K 50/75
A61K 31/132
A61K 31/136
A61K 31/164
Applicants
  • THE UNIVERSITY OF NOTTINGHAM [GB/GB]; University Park Nottingham Nottinghamshire NG7 2RD, GB
Inventors
  • MAHDAVI, Jafar; GB
  • ALA' ALDEEN, Dlawer; GB
Agents
  • BARKER BRETTELL LLP; 100 Hagley Road Edgbaston Birmingham West Midlands B16 8QQ, GB
Priority Data
1202681.116.02.2012GB
1220158.808.11.2012GB
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) REDUCTION OF GASTROINTESTINAL TRACT COLONISATION BY CAMPYLOBACTER
(FR) RÉDUCTION DE LA COLONISATION DU TRACTUS GASTRO-INTESTINAL PAR CAMPYLOBACTÉRIE
Abstract
(EN)
Campylobacterare the commonest reported bacterial causes of gastroenteritis in the UK and industrialized world. This invention relates to a method of preventing or reducing the colonisation of the gastrointestinal tract of an animal with Campylobacter. Accordingly, the present invention provides a method for disinfection of an animal comprising administering to said animal at least one compound that binds to MOMP or FlaA of Campylobacter in an effective amount to reduce the number of Campylobacter present in the gastrointestinal tract of said animal. The present invention also provides a method for preventing or reducing transmission of Campylobacter infection from one animal to another.
(FR)
L'invention concerne des campylobactéries qui sont les causes bactériennes rapportées les plus courantes de gastroentérite au Royaume-Uni et dans le mode industrialisé. La présente invention concerne un procédé de prévention ou de réduction de la colonisation du tractus gastro-intestinal d'un animal par une campylobactérie. Par conséquent, la présente invention concerne un procédé de désinfection d'un animal comprenant l'administration audit animal d'au moins un composé qui se lie à MOMP ou FlaA de campylobactérie dans une quantité efficace pour réduire le nombre de campylobactéries présentes dans le tractus gastro-intestinal dudit animal. La présente invention concerne également un procédé de prévention ou de réduction de la transmission d'une infection par campylobactérie d'un animal à un autre.
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