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1. (WO2013120995) EXOSOMAL BIOMARKER FOR CARDIOVASCULAR EVENTS IN FEMALES
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2013/120995 International Application No.: PCT/EP2013/053078
Publication Date: 22.08.2013 International Filing Date: 15.02.2013
IPC:
G01N 33/50 (2006.01)
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
Applicants:
CAVADIS B.V. [NL/NL]; Catherijnesingel 52 NL-3511 GC Utrecht, NL
Inventors:
DE KLEIJN, Dominique; SG
PASTERKAMP, Gerard; NL
Agent:
HATEBOER, Guus; DeltaPatents B.V. Fellenoord 370 5611 ZL Eindhoven, NL
Priority Data:
12191411.306.11.2012EP
PCT/EP2012/00071517.02.2012EP
PCT/EP2012/06613417.08.2012EP
Title (EN) EXOSOMAL BIOMARKER FOR CARDIOVASCULAR EVENTS IN FEMALES
(FR) BIOMARQUEUR EXOSOMAL POUR ÉVÉNEMENTS CARDIOVASCULAIRES CHEZ LA FEMME
Abstract:
(EN) The invention relates to methods of determining, in respect of a female subject, the risk of developing a cardiovascular event, such as coronary artery disease, by measuring SerpinF2 protein levels in a bodily fluid sample comprising exosomes from said female subject and determining whether said level indicates whether said female subject is at risk of developing a cardiovascular event.
(FR) La présente invention concerne des méthodes de détermination, chez une patiente, du risque de développement d'un événement cardiovasculaire, notamment une maladie artérielle coronarienne, en mesurant les taux de protéine SerpinF2 dans un échantillon de liquide corporel comprenant des exosomes de ladite patiente et en déterminant si ledit taux indique si ladite patiente risque de développer un événement cardiovasculaire.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)