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|1. (WO2013120058) NOVEL SP-B & SP-C PEPTIDES, SYNTHETIC LUNG SURFACTANTS, AND USE THEREOF|
|Applicants:||UNIVERSITY OF ROCHESTER
LOS ANGELES BIOMEDICAL RESEARCH INSTITUTE AT HARBOR
|Inventors:||WALTHER, Frans, J.
GORDON, Larry, M.
WARING, Alan, J.
NOTTER, Robert, H.
|Title:||NOVEL SP-B & SP-C PEPTIDES, SYNTHETIC LUNG SURFACTANTS, AND USE THEREOF|
The present invention relates to synthetic lung surfactant compositions that include a novel surface active peptide and a phospholipid, including phospholipase-resistant phospho-glycerol derivatives, phospholipase-resistant phospho-choline derivatives, naturally occurring phospholipids, or a combination thereof. Uses of the surfactant compositions of the present invention to treat endogenous surfactant dysfunctional or deficient lung tissue and to deliver therapeutic agents are also disclosed.