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Machine translation
1. (WO2013120058) NOVEL SP-B & SP-C PEPTIDES, SYNTHETIC LUNG SURFACTANTS, AND USE THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2013/120058    International Application No.:    PCT/US2013/025532
Publication Date: 15.08.2013 International Filing Date: 11.02.2013
IPC:
A61K 38/00 (2006.01), A61K 9/127 (2006.01), C07K 14/785 (2006.01), C07K 14/00 (2006.01)
Applicants: UNIVERSITY OF ROCHESTER [US/US]; 601 Elmwood Avenue Box Ott Rochester, NY 14642 (US).
LOS ANGELES BIOMEDICAL RESEARCH INSTITUTE AT HARBOR; Ucla Medical Center 1124 W. Carson Street Torrance, CA 90502 (US)
Inventors: WALTHER, Frans, J.; (US).
GORDON, Larry, M.; (US).
WARING, Alan, J.; (US).
WANG, Zhengdong; (US).
NOTTER, Robert, H.; (US)
Agent: GOLDMAN, Michael, L.; Leclairryan 70 Linden Oaks Rochester, NY 14625 (US)
Priority Data:
61/596,913 09.02.2012 US
Title (EN) NOVEL SP-B & SP-C PEPTIDES, SYNTHETIC LUNG SURFACTANTS, AND USE THEREOF
(FR) NOUVEAUX PEPTIDES SP-B ET SP-C, TENSIOACTIFS PULMONAIRES SYNTHÉTIQUES, ET LEURS UTILISATIONS
Abstract: front page image
(EN)The present invention relates to synthetic lung surfactant compositions that include a novel surface active peptide and a phospholipid, including phospholipase-resistant phospho-glycerol derivatives, phospholipase-resistant phospho-choline derivatives, naturally occurring phospholipids, or a combination thereof. Uses of the surfactant compositions of the present invention to treat endogenous surfactant dysfunctional or deficient lung tissue and to deliver therapeutic agents are also disclosed.
(FR)La présente invention concerne des compositions de tensioactifs pulmonaires synthétiques qui comportent un nouveau peptide actif de surface et un phospholipide, comprenant des dérivés de phosphoglycérol résistants à la phospholipase, des dérivés de phosphocholine résistants à la phospholipase, des phospholipides naturels, ou une combinaison de ceux-ci. L'invention porte également sur des utilisations desdites compositions de tensioactifs pour traiter les tissus pulmonaires à tensioactifs endogènes dysfonctionnant ou déficients et pour procurer des agents thérapeutiques.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)