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1. (WO2013119979) METHODS AND COMPOSITIONS FOR MODULATING FACTOR VII EXPRESSION
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2013/119979 International Application No.: PCT/US2013/025381
Publication Date: 15.08.2013 International Filing Date: 08.02.2013
IPC:
C12N 15/11 (2006.01) ,C07H 21/04 (2006.01)
Applicants: ISIS PHARMACEUTICALS, INC.[US/US]; 2855 Gazelle Court Carlsbad, CA 92010, US
Inventors: SWAYZE, Eric, E.; US
FREIER, Susan, M.; US
Agent: GINGRICH, Brenden; Knobbe Martens 2040 Main Street, 14th Floor Irvine, CA 92614, US
Priority Data:
61/596,68808.02.2012US
Title (EN) METHODS AND COMPOSITIONS FOR MODULATING FACTOR VII EXPRESSION
(FR) MÉTHODES ET COMPOSITIONS PERMETTANT DE MODULER L'EXPRESSION DU FACTEUR VII
Abstract:
(EN) Disclosed herein are antisense compounds and methods for decreasing Factor VII and treating, preventing, or slowing progression of thromboembolic complications, hyperproliferative disorders, or inflammatory conditions in an individual in need thereof.
(FR) La présente invention concerne des composés antisens et des méthodes permettant, chez un individu en ayant besoin, d'inhiber le facteur VII et de traiter ou prévenir les complications thromboemboliques, les troubles hyperprolifératifs ou les affections inflammatoires ou, encore, d'en ralentir la progression.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)