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1. (WO2013119947) PEPMIXES TO GENERATE MULTIVIRAL CTLS WITH BROAD SPECIFICITY
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2013/119947    International Application No.:    PCT/US2013/025342
Publication Date: 15.08.2013 International Filing Date: 08.02.2013
IPC:
C12N 15/00 (2006.01), A01N 63/00 (2006.01)
Applicants: BAYLOR COLLEGE OF MEDICINE [US/US]; Baylor College of Medicine One Baylor Plaza Houston, TX 77030 (US)
Inventors: LEEN, Anne, Marie; (US).
VALDES, Juan, Fernando Vera; (US).
ROONEY, Cliona, M.; (US).
GERDEMANN, Ulrike; (US)
Agent: SISTRUNK, Melissa, L.; Fulbright & Jaworski, L.L.P Fulbright Tower 1301 Mckinney, Suite 5100 Houston, TX 77010-3095 (US)
Priority Data:
61/596,875 09.02.2012 US
Title (EN) PEPMIXES TO GENERATE MULTIVIRAL CTLS WITH BROAD SPECIFICITY
(FR) MÉLANGE DE PEPTIDES POUR PRODUIRE DES CTLMULTIVIRAUX AVEC UNE LARGE SPÉCIFICITÉ
Abstract: front page image
(EN)The present invention concerns methods of generating CTLs that are able to target at least one antigen from two or more viruses. The method includes exposing mixtures of peptides for different antigens to the same plurality of PBMCs and, at least in certain aspects, expanding the cells in the presence of IL4 and IL7.
(FR)La présente invention concerne des procédés pour générer des CTL capables de cibler au moins un antigène provenant d'au moins deux virus. Le procédé consiste à exposer des mélanges de peptides pour des antigènes différents à la même pluralité de PBMC et, au moins dans certains aspects, à dilater les cellules en présence d'IL4 et d'IL7.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)