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1. (WO2013119772) PRODUCTS OF MANUFACTURE HAVING TANTALUM COATED NANOSTRUCTURES, AND METHODS OF MAKING AND USING THEM

Pub. No.:    WO/2013/119772    International Application No.:    PCT/US2013/025090
Publication Date: Fri Aug 16 01:59:59 CEST 2013 International Filing Date: Fri Feb 08 00:59:59 CET 2013
IPC: A61L 27/30
A61L 27/38
A61F 2/28
Applicants: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Inventors: JIN, Sungho
FRANDSEN, Christine
Title: PRODUCTS OF MANUFACTURE HAVING TANTALUM COATED NANOSTRUCTURES, AND METHODS OF MAKING AND USING THEM
Abstract:
In alternative embodiments, the invention provides products (articles) of manufacture comprising nanostructures such as nanotubes having a surface comprising tantalum. In alternative embodiments, products of manufacture of the invention include nanostructures, e.g., nanotubes, nanowire, nanopore, and the like comprising a surface layer of tantalum. In alternative embodiments, products or articles of manufacture of the invention are bioimplants, and the tantalum-surface-coated nanostructures of the invention provide increased bioactivity and bone forming ability. In alternative embodiments, products or articles of manufacture of the invention, e.g., bioimplants, comprising the tantalum-surface-coated nanostructures of the invention are used for in vitro, ex vivo and in vivo testing, implants, biomedical devices and therapeutics.