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1. (WO2013119677) PHARMACEUTICAL COMPOSITIONS CONTAINING DIMETHYL FUMARATE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2013/119677    International Application No.:    PCT/US2013/024946
Publication Date: 15.08.2013 International Filing Date: 06.02.2013
IPC:
A61K 31/225 (2006.01)
Applicants: BIOGEN IDEC MA INC. [US/US]; 14 Cambridge Center Cambridge, MA 02142 (US)
Inventors: GOLDMAN, David; (US).
DAWSON, Katherine; (US).
NIRULA, Ajay; (US)
Agent: COVERT, John, M.; Sterne Kessler Goldstein & Fox PLLC 1100 New York Avenue, N.W. Washington, DC 20005 (US)
Priority Data:
61/723,048 06.11.2012 US
61/625,621 17.04.2012 US
61/596,202 07.02.2012 US
Title (EN) PHARMACEUTICAL COMPOSITIONS CONTAINING DIMETHYL FUMARATE
(FR) COMPOSITIONS PHARMACEUTIQUES CONTENANT DU FUMARATE DE DIMÉTHYLE
Abstract: front page image
(EN)Provided herein are compositions containing compounds, or pharmaceutically acceptable salts, that metabolize to monomethyl fumarate with certain pharmacokinetic parameters and methods for treating, prophylaxis, or amelioration of neurodegenerative diseases including multiple sclerosis using such compositions in a subject, wherein if the compositions contain dimethyl fumarate, the total amount of dimethyl fumarate in the compositions ranges from about 43% w/w to about 95% w/w.
(FR)La présente invention concerne des compositions contenant des composés, ou des sels pharmaceutiquement acceptables de ceux-ci, qui sont métabolisés en fumarate de monométhyle ayant certains paramètres pharmacocinétiques et des procédés pour le traitement, la prophylaxie, ou l'amélioration de maladies neurodégénératives comprenant la sclérose en plaques utilisant de telles compositions chez un sujet, où, si les compositions contiennent du fumarate de diméthyle, la quantité totale de fumarate de diméthyle dans les compositions est dans la plage d'environ 43 % m/m à environ 95 % m/m.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)