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1. (WO2013118452) CALCIUM PHOSPHATE DISPERSION COMPOSITION
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2013/118452 International Application No.: PCT/JP2013/000433
Publication Date: 15.08.2013 International Filing Date: 28.01.2013
IPC:
A61K 8/24 (2006.01) ,A23L 1/30 (2006.01) ,A23L 1/304 (2006.01) ,A61K 8/04 (2006.01) ,A61K 8/37 (2006.01) ,A61K 8/44 (2006.01) ,A61K 8/73 (2006.01) ,A61K 9/10 (2006.01) ,A61K 33/42 (2006.01) ,A61K 47/14 (2006.01) ,A61K 47/18 (2006.01) ,A61K 47/36 (2006.01) ,A61P 1/02 (2006.01) ,A61Q 11/00 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8
Cosmetics or similar toilet preparations
18
characterised by the composition
19
containing inorganic ingredients
24
Phosphorus; Compounds thereof
A HUMAN NECESSITIES
23
FOODS OR FOODSTUFFS; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES
L
FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D91; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
1
Foods or foodstuffs; Their preparation or treatment
29
Modifying nutritive qualities of foods; Dietetic products
30
containing additives
A HUMAN NECESSITIES
23
FOODS OR FOODSTUFFS; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES
L
FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D91; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
1
Foods or foodstuffs; Their preparation or treatment
29
Modifying nutritive qualities of foods; Dietetic products
30
containing additives
304
Inorganic salts, minerals, trace elements
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8
Cosmetics or similar toilet preparations
02
characterised by special physical form
04
Dispersions; Emulsions
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8
Cosmetics or similar toilet preparations
18
characterised by the composition
30
containing organic compounds
33
containing oxygen
37
Esters of carboxylic acids
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8
Cosmetics or similar toilet preparations
18
characterised by the composition
30
containing organic compounds
40
containing nitrogen
44
Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts, esters or N-acylated derivatives thereof
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8
Cosmetics or similar toilet preparations
18
characterised by the composition
72
containing organic macromolecular compounds
73
Polysaccharides
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
10
Dispersions; Emulsions
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
33
Medicinal preparations containing inorganic active ingredients
42
Phosphorus; Compounds thereof
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
06
Organic compounds
08
containing oxygen
14
Esters of carboxylic acids
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
06
Organic compounds
16
containing nitrogen
18
Amines; Quaternary ammonium compounds
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
30
Macromolecular compounds
36
Polysaccharides; Derivatives thereof
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
1
Drugs for disorders of the alimentary tract or the digestive system
02
Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
Q
SPECIFIC USE OF COSMETICS OR SIMILAR TOILET PREPARATIONS
11
Preparations for care of the teeth, of the oral cavity or of dentures, e.g. dentifrices or toothpastes; Mouth rinses
Applicants:
株式会社サンギ KABUSHIKI KAISHA SANGI [JP/JP]; 東京都中央区築地3丁目11番6号 11-6, Tsukiji 3-chome, Chuo-ku, Tokyo 1048440, JP
Inventors:
藤田 恵二郎 FUJITA, Keijiro; JP
小吹 真理子 OBUKI, Mariko; JP
斎藤 宗輝 SAITO, Tomoki; JP
佐久間 周治 SAKUMA, Shuji; JP
Agent:
廣田 雅紀 HIROTA, Masanori; 東京都港区赤坂二丁目2番19号アドレスビル6階 6th Fl. Address Bldg., 2-2-19, Akasaka, Minato-ku, Tokyo 1070052, JP
Priority Data:
2012-02446507.02.2012JP
Title (EN) CALCIUM PHOSPHATE DISPERSION COMPOSITION
(FR) COMPOSITION DE DISPERSION DE PHOSPHATE DE CALCIUM
(JA) リン酸カルシウム分散組成物
Abstract:
(EN) The present invention addresses the problem of providing a liquid oral composition or liquid food composition in which a calcium phosphate, such as a hydroxyapatite or tricalcium phosphate, is in a stably dispersed state and can be prevented from sedimenting or separating out even in long-term storage. By adding xanthane gum and a polyglycerol fatty acid ester to a calcium phosphate, the calcium phosphate is rendered stably dispersed even in long-term storage, and the calcium phosphate can be prevented from sedimenting or separating out even when used in liquid oral compositions such as a mouthwash, liquid dentifrice, and oral detergent or in liquid food compositions such as milk, soy milk, yoghurt, and a refreshing beverage. Furthermore, by incorporating an amphoteric surfactant besides the xanthane gum and polyglycerol fatty acid ester, the calcium phosphate contained in a liquid oral composition such as a mouthwash, liquid dentifrice, or oral detergent can be more effectively prevented from sedimenting or separating out.
(FR) La présente invention traite du problème visant à fournir une composition orale liquide ou une composition alimentaire liquide dans laquelle un phosphate de calcium, tel qu'une hydroxyapatite, se trouve dans un état dispersé de manière stable et peut être empêché de laisser se sédimenter ou séparer même dans un stockage de longue durée. En ajoutant de la gomme xanthane et un ester d'acide gras et de polyglycérol à un phosphate de calcium, le phosphate de calcium est rendu dispersé de façon stable même dans un stockage à long terme, et il est plus facile de l'empêcher de se sédimenter ou de se séparer même lorsqu'il est utilisé dans des compositions liquides à usage oral telles qu'un bain de bouche, un dentifrice liquide, et un détergent buccal ou dans des compositions d'aliments liquides telles que du lait, du yaourt, du lait de soja, et une boisson rafraîchissante. En outre, en incorporant un agent tensioactif amphotère en plus de la gomme de xanthane et de l'ester d'acide gras et de polyglycérol, il est plus facile d'empêcher le phosphate de calcium contenu dans une composition liquide à usage oral telle qu'un bain de bouche, un dentifrice liquide ou un détergent buccal de se sédimenter ou de se séparer.
(JA)  長期間の保管においてもハイドロキシアパタイトやリン酸三カルシウムなどのリン酸カルシウムを安定に分散し、沈殿や分離を防止し得る液状の口腔組成物や液状の食品組成物を提供することを課題とする。リン酸カルシウムに、キサンタンガム、ポリグリセリン脂肪酸エステルを配合することにより、長期間の保管においてもリン酸カルシウムが安定に分散し、洗口剤、液体歯磨剤、口腔洗浄剤などの液状口腔組成物や、牛乳、豆乳、ヨーグルト、清涼飲料などの液状食品組成物に使用しても、リン酸カルシウムの沈殿、分離を防止することができる。更に、両性界面活性剤を、キサンタンガム、ポリグリセリン脂肪酸エステルに加えて配合することにより、洗口剤、液体歯磨剤、口腔洗浄剤などの液状口腔組成物におけるリン酸カルシウムの沈殿や分離を一層防止することができる。
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)