WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO2013117969) PROCESS FOR PREPARING STABLE PHARMACEUTICAL COMPOSITIONS OF COMPOUNDS SUSCEPTIBLE TO HYDROLYSIS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2013/117969    International Application No.:    PCT/IB2012/051513
Publication Date: 15.08.2013 International Filing Date: 29.03.2012
Chapter 2 Demand Filed:    26.11.2013    
IPC:
A61K 9/19 (2006.01), A61K 31/4184 (2006.01), A61K 31/706 (2006.01)
Applicants: FRESENIUS KABI ONCOLOGY LTD. [IN/IN]; B - 310, Som Datt Chambers - I Bhikaji Cama Place, New Delhi 110 066 (IN) (For All Designated States Except US).
KHATTAR, Dhiraj [IN/IN]; (IN) (For US Only).
KHANNA, Rajesh [IN/IN]; (IN) (For US Only).
MOTWANI, Sanjay [IN/IN]; (IN) (For US Only).
GARG, Minakshi [IN/IN]; (IN) (For US Only).
CHANDEL, Vikas [IN/IN]; (IN) (For US Only).
YADAV, Mukti [IN/IN]; (IN) (For US Only).
KUMAR KYAMA, Vijay [IN/IN]; (IN) (For US Only).
BHANDARI, Vikas [IN/IN]; (IN) (For US Only)
Inventors: KHATTAR, Dhiraj; (IN).
KHANNA, Rajesh; (IN).
MOTWANI, Sanjay; (IN).
GARG, Minakshi; (IN).
CHANDEL, Vikas; (IN).
YADAV, Mukti; (IN).
KUMAR KYAMA, Vijay; (IN).
BHANDARI, Vikas; (IN)
Agent: PRACHI, Tiwari; Fresenius Kabi Oncology Limited Echelon Institutional Area Plot N°. 11, Sector-32 Gurgaon 122 001 Haryana (IN)
Priority Data:
337/DEL/2012 06.02.2012 IN
Title (EN) PROCESS FOR PREPARING STABLE PHARMACEUTICAL COMPOSITIONS OF COMPOUNDS SUSCEPTIBLE TO HYDROLYSIS
(FR) PROCÉDÉ POUR PRÉPARER DES COMPOSITIONS PHARMACEUTIQUES STABLES DE COMPOSÉS SENSIBLES À L'HYDROLYSE
Abstract: front page image
(EN)The present invention relates to a process of preparing a stable pharmaceutical composition of compounds which are susceptible to hydrolysis comprising a. Addition of required quantity of pharmaceutically acceptable lyophilization excipients optionally in Water for Injection in a formulation vessel; b. Addition of organic solvent to form a appropriate proportion of aqueous and organic solvent; c. Maintaining the temperature of the formulation vessel from the range -5±1°C to - 5±3°C; d. Addition of required quantity of compound susceptible to hydrolysis to form a solution and lyophilizing the solution.
(FR)La présente invention concerne un procédé de préparation d'une composition pharmaceutique stable de composés qui sont sensibles à l'hydrolyse comprenant a. l'ajout d'une quantité requise d'excipients de lyophilisation pharmaceutiquement acceptables facultativement dans de l'eau pour injection dans une cuve de formulation ; b. l'ajout de solvant organique pour former une proportion appropriée de solvant aqueux et organique ; c. le maintien de la température de la cuve de formulation dans la plage de -5±1 °C à -5±3 °C ; d. l'ajout de la quantité requise de composé sensible à l'hydrolyse pour former une solution et la lyophilisation de la solution.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)