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1. (WO2013117735) CONJUGATE COMPRISING AN AGENT AND AN ANTIVIRAL LIGAND AND ITS USE IN A METHOD FOR DELIVERING THE AGENT INTRACELLULARLY
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2013/117735    International Application No.:    PCT/EP2013/052607
Publication Date: 15.08.2013 International Filing Date: 08.02.2013
IPC:
A61K 47/48 (2006.01), A61P 31/12 (2006.01), C07K 16/08 (2006.01), A61K 31/337 (2006.01)
Applicants: MEDICAL RESEARCH COUNCIL [GB/GB]; 2nd Floor David Phillips Building Polaris House, North Star Avenue, Wiltshire Swindon SN2 1FL (GB)
Inventors: JAMES, Leo; (GB)
Agent: MASCHIO, Antonio; Maschio & Soames IP Limited 20 Carlton Crescent Southampton Hampshire SO15 2ET (GB)
Priority Data:
1202268.7 09.02.2012 GB
Title (EN) CONJUGATE COMPRISING AN AGENT AND AN ANTIVIRAL LIGAND AND ITS USE IN A METHOD FOR DELIVERING THE AGENT INTRACELLULARLY
(FR) CONJUGUÉ COMPRENANT UN AGENT ET UN LIGAND ANTIVIRAL, ET SON UTILISATION DANS UN PROCÉDÉ D'ADMINISTRATION DE L'AGENT PAR VOIE INTRACELLULAIRE
Abstract: front page image
(EN)There is provided a method for killing virally infected cells comprising exposing cells to an a cytotoxic agent conjugated to a virus-specific ligand, in the presence of the virus which infects the cells. Conjugates and intracellular complexes comprising virus and cytotoxic agents are also provided.
(FR)L'invention concerne un procédé de destruction de cellules infectées par un virus en les exposant à un agent cytotoxique conjugué à un ligand spécifique au virus, en présence du virus infectant les cellules. L'invention porte également sur des conjugués et des complexes intracellulaires comprenant un virus et des agents cytotoxiques.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)