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1. (WO2013117631) PENTOSE FERMENTING MICROORGANISMS

Pub. No.:    WO/2013/117631    International Application No.:    PCT/EP2013/052407
Publication Date: Fri Aug 16 01:59:59 CEST 2013 International Filing Date: Fri Feb 08 00:59:59 CET 2013
IPC: C12N 9/90
C12P 7/06
C12P 19/24
Applicants: CLARIANT PRODUKTE (DEUTSCHLAND) GMBH
Inventors: DRAGOVIC, Zdravko
GAMAUF, Christian
REISINGER, Christoph
KETTLING, Ulrich
Title: PENTOSE FERMENTING MICROORGANISMS
Abstract:
The invention provides a microbial eukaryotic cell capable of utilizing C5 sugars, in particular xylose. Another objective of the invention is to provide an improved protein sequence to enable eukaryotic cells to degrade C5 sugars. The present invention thus provides protein comprising an amino acid sequence having at least 75% identity, preferably 80% identity, most preferably 90 % identity, most highly preferably 95 % identity to SEQ ID NO. 2 or SEQ ID NO. 8 and having xylose-isomerase activity in a eukaryotic cell.