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1. (WO2013117288) TETRAHYDRO-QUINAZOLINONE DERIVATIVES AS TANK AND PARP INHIBITORS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2013/117288    International Application No.:    PCT/EP2013/000078
Publication Date: 15.08.2013 International Filing Date: 14.01.2013
IPC:
C07D 403/12 (2006.01), C07D 401/04 (2006.01), C07D 401/12 (2006.01), C07D 239/95 (2006.01), A61K 31/517 (2006.01), A61P 35/00 (2006.01), A61P 29/00 (2006.01), A61P 25/00 (2006.01)
Applicants: MERCK PATENT GMBH [DE/DE]; Frankfurter Strasse 250 64293 Darmstadt (DE)
Inventors: BUCHSTALLER, Hans-Peter; (DE).
ESDAR, Christina; (DE).
LEUTHNER, Birgitta; (DE)
Priority Data:
12000841.2 09.02.2012 EP
Title (EN) TETRAHYDRO-QUINAZOLINONE DERIVATIVES AS TANK AND PARP INHIBITORS
(FR) DÉRIVÉS TÉTRAHYDRO-QUINAZOLINONE COMME INHIBITEURS DE TANK ET DE PARP
Abstract: front page image
(EN)Compounds of the formula I in which U, V and W have the meanings indicated in Claim 1, are inhibitors of Tankyrase, and can be employed, inter alia, for the treatment of diseases such as cancer, cardiovascular diseases, central nervous system injury and different forms of inflammation.
(FR)La présente invention concerne des composés de formule I dans laquelle U, V et W ont les significations indiquées dans la revendication 1, qui sont des inhibiteurs de la tankyrase, et qui peuvent être utilisés, entre autres, pour le traitement de maladies comme le cancer, les maladies cardiovasculaires, les lésions du système nerveux central et différentes formes d'inflammation.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)