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1. (WO2013117285) FURO [3, 2 - B] - AND THIENO [3, 2 - B] PYRIDINE DERIVATIVES AS TBK1 AND IKK INHIBITORS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2013/117285    International Application No.:    PCT/EP2013/000006
Publication Date: 15.08.2013 International Filing Date: 03.01.2013
IPC:
C07D 493/04 (2006.01), C07D 495/04 (2006.01), A61K 31/4355 (2006.01), A61K 31/4365 (2006.01), A61P 35/00 (2006.01), A61P 19/02 (2006.01), A61P 17/06 (2006.01), A61P 25/28 (2006.01), A61P 27/06 (2006.01)
Applicants: MERCK PATENT GMBH [DE/DE]; Frankfurter Strasse 250 64293 Darmstadt (DE)
Inventors: EGGENWEILER, Hans-Michael; (DE).
HOELZEMANN, Guenter; (DE).
DORSCH, Dieter; (DE)
Priority Data:
12000842.0 09.02.2012 EP
Title (EN) FURO [3, 2 - B] - AND THIENO [3, 2 - B] PYRIDINE DERIVATIVES AS TBK1 AND IKK INHIBITORS
(FR) DÉRIVÉS DE LA FURO[3,2-B]- ET DE LA THIÉNO[3,2-B] PYRIDINE COMME INHIBITEURS DE TBK1 ET IKK
Abstract: front page image
(EN)Compounds of the formula (I) in which R1, R2 and X have the meanings indicated in Claim 1, are inhibitors of TBK1 and ΙΚΚε and can be employed, inter alia, for the treatment of cancer and inflammatory diseases.
(FR)La présente invention concerne des composés de formule (I) dans laquelle R1, R2 et X ont les significations indiquées dans la revendication 1, qui sont des inhibiteurs de TBK1 et ΙΚΚε et qui peuvent être utilisés, entre autres, pour le traitement du cancer et des maladies inflammatoires.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)