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1. (WO2013116822) METHODS AND COMPOSITIONS FOR TREATING GASTRIC DISORDERS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2013/116822    International Application No.:    PCT/US2013/024596
Publication Date: 08.08.2013 International Filing Date: 04.02.2013
IPC:
A61K 9/127 (2006.01), A61K 39/08 (2006.01), A61P 1/12 (2006.01)
Applicants: LIPELLA PHARMACEUTICALS, INC. [US/US]; 400 N. Lexington Avenue, Suite Ll103 Pittsburgh, PA 15208 (US)
Inventors: CHANCELLOR, Michael, B.; (US).
KAUFMAN, Jonathan, H.; (US)
Agent: PABST, Patrea L.; Pabst Patent Group LLP 1545 Peachtree Street, N.E. Suite 320 Atlanta, GA 30309 (US)
Priority Data:
61/594,088 02.02.2012 US
61/594,092 02.02.2012 US
13/368,186 07.02.2012 US
Title (EN) METHODS AND COMPOSITIONS FOR TREATING GASTRIC DISORDERS
(FR) PROCÉDÉS ET COMPOSITIONS POUR LE TRAITEMENT DE TROUBLES GASTRIQUES
Abstract: front page image
(EN)Improved efficacy in treatment of gastric disorders with botulinum toxin is obtained using liposomal encapsulated botulinum formulations for topical administration of the botulinum toxin. The liposomes are typically administered in a physiologically acceptable carrier such as saline or phosphate buffered saline by application onto the surface of the tissue within into the gastrointestinal (GI) tract in need of treatment. Preferably, the formulation is applied via a roller, sponge or nozzle that is attached to an endoscope.
(FR)L'invention concerne une amélioration de l'efficacité du traitement de troubles gastriques par la toxine botulique par l'utilisation de formulations botuliques encapsulées liposomales destinées à l'administration topique de la toxine botulique. Les liposomes sont, de manière caractéristique, administrés dans un support physiologiquement acceptable, tel que du sérum physiologique ou du sérum physiologique tamponné au phosphate, par application sur la surface du tissu dans le tractus gastro-intestinal (GI) d'un patient qui a besoin de tel traitement. De préférence, la formulation est appliquée via un rouleau, une éponge ou une canule qui est fixé(e) à un endoscope.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)