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1. (WO2013116822) METHODS AND COMPOSITIONS FOR TREATING GASTRIC DISORDERS

Pub. No.:    WO/2013/116822    International Application No.:    PCT/US2013/024596
Publication Date: Fri Aug 09 01:59:59 CEST 2013 International Filing Date: Tue Feb 05 00:59:59 CET 2013
IPC: A61K 9/127
A61K 39/08
A61P 1/12
Applicants: LIPELLA PHARMACEUTICALS, INC.
Inventors: CHANCELLOR, Michael, B.
KAUFMAN, Jonathan, H.
Title: METHODS AND COMPOSITIONS FOR TREATING GASTRIC DISORDERS
Abstract:
Improved efficacy in treatment of gastric disorders with botulinum toxin is obtained using liposomal encapsulated botulinum formulations for topical administration of the botulinum toxin. The liposomes are typically administered in a physiologically acceptable carrier such as saline or phosphate buffered saline by application onto the surface of the tissue within into the gastrointestinal (GI) tract in need of treatment. Preferably, the formulation is applied via a roller, sponge or nozzle that is attached to an endoscope.