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1. (WO2013116753) FATTY ACIDS AS ANTI-INFLAMMATORY AGENTS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2013/116753    International Application No.:    PCT/US2013/024476
Publication Date: 08.08.2013 International Filing Date: 01.02.2013
IPC:
A61K 31/202 (2006.01), A61K 31/20 (2006.01), A61P 29/00 (2006.01)
Applicants: UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION [US/US]; 200 Gardner Steel Conference Center Thackeray And O'Hara Streets Pittsburgh, PA 15260 (US)
Inventors: FREEMAN, Bruce, A.; (US).
SCHOPFER, Francisco, J.; (US)
Agent: RUPERT, Wayne; Klarquist Sparkman, LLP One World Trade Center, Suite 1600 121 SW Salmon Street Portland, OR 97204 (US)
Priority Data:
61/594,911 03.02.2012 US
Title (EN) FATTY ACIDS AS ANTI-INFLAMMATORY AGENTS
(FR) ACIDES GRAS COMME AGENTS ANTI-INFLAMMATOIRES
Abstract: front page image
(EN)A class of enzymatically generated electrophilic fatty acid derivatives (EFADs), or their enzymatically generated metabolites. The EFAD's and their metabolites have beneficial effects human health. According to the inventors the inventive keto fatty acids or their enzymatically generated metabolites, can inhibit inflammation by giving rise to adaptive signaling molecules in vivo.
(FR)La présente invention concerne une classe de dérivés d'acides gras électrophiles (EFAD) d'origine enzymatique ou leurs métabolites d'origine enzymatique. Les EFAD et leurs métabolites ont des effets bénéfiques sur la santé humaine. Selon les inventeurs, les acides gras cétoniques de l'invention ou leurs métabolites d'origine enzymatique peuvent inhiber l'inflammation en donnant lieu à des molécules de signalisation adaptatives in vivo.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)