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1. (WO2013116705) COMPOSITE ASSAY FOR DETECTING A CLINICAL CONDITION

Pub. No.:    WO/2013/116705    International Application No.:    PCT/US2013/024419
Publication Date: Fri Aug 09 01:59:59 CEST 2013 International Filing Date: Sat Feb 02 00:59:59 CET 2013
IPC: C12Q 1/68
C12N 5/00
C12N 5/02
Applicants: PREDICTIVE BIOSCIENCES, INC.
Inventors: SHUBER, Anthony, P.
Title: COMPOSITE ASSAY FOR DETECTING A CLINICAL CONDITION
Abstract:
The invention generally relates to methods for screening patients for one or more clinical conditions using a composite assay. According to certain aspects, methods of the invention involve isolating at least one nucleic acid from a biological sample obtained from the subject, detecting at least one sequence mutation and a chromosomal abnormality in the at least one nucleic acid in a single assay format, and identifying a clinical condition in said subject when both the sequence mutation and the chromosomal abnormality are present.