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1. (WO2013116677) ASSAYS FOR DETECTION OF GLYCOSAMINOGLYCANS
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2013/116677 International Application No.: PCT/US2013/024379
Publication Date: 08.08.2013 International Filing Date: 01.02.2013
IPC:
C12Q 1/56 (2006.01) ,C08B 37/10 (2006.01)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
Q
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1
Measuring or testing processes involving enzymes or micro-organisms; Compositions therefor; Processes of preparing such compositions
56
involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen
C CHEMISTRY; METALLURGY
08
ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
B
POLYSACCHARIDES; DERIVATIVES THEREOF
37
Preparation of polysaccharides not provided for in groups C08B1/-C08B35/110; Derivatives thereof
10
Heparin; Derivatives thereof
Applicants: SHIRE HUMAN GENETIC THERAPIES, INC.[US/US]; 300 Shire Way Lexington, MA 02421, US
Inventors: RUIZ, Juan; US
SELLOS-MOURA, Marcia; US
SHI, Philip; US
Agent: TREANNIE, Lisa, M.; Morse, Barnes-Brown & Pendleton, P.C. Citypoint 230 Third Avenue, 4th Floor Waltham, MA 02451, US
Priority Data:
61/593,77701.02.2012US
Title (EN) ASSAYS FOR DETECTION OF GLYCOSAMINOGLYCANS
(FR) DOSAGES POUR LA DÉTECTION DE GLYCOSAMINOGLYCANES
Abstract:
(EN) Disclosed herein are novel methods, assays and kits useful for the diagnosis and monitoring of subjects with mucopolysaccharidoses (MPS). The methods, assays and kits are particularly useful for detecting the presence of one or more glycosaininoglycans which correlate to MPS and its severity in a variety of biological samples.
(FR) La présente invention concerne des nouveaux procédés, dosages et kits utiles pour le diagnostic et la surveillance de patients atteints de mucopolysaccharidoses (MPS). Les procédés, dosages et kits sont particulièrement utiles pour la détection de la présence d'un ou de plusieurs glycosaminoglycanes qui sont associés à une MPS et à sa sévérité dans une variété d'échantillons biologiques.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)